Results 171 to 180 of about 741,842 (292)

A reference standard for genome biology [PDF]

Nature Biotechnology, 2018
openaire   +2 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

First establishment of population-specific brain volume reference standards for Chinese children and adolescents: an AI-based segmentation study. [PDF]

Front Pediatr
Qian H, Liao J, Cheng J.
europepmc   +1 more source

Differences in Molecular Subtype Reference Standards Impact AI-based Breast Cancer Classification with Dynamic Contrast-enhanced MRI. [PDF]

Radiology, 2023
Ji Y, Whitney HM, Li H, Liu P, Giger ML, Zhang X.   +5 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

A comparison of blood pressure reference values and the prevalence of high blood pressure in Indian adolescents aged 10-16 years using American and Indian reference standards. [PDF]

Clin Hypertens
Saji A, Thomas T, Sachdev HS, Kurpad AV, Vasudevan A.   +4 more
europepmc   +1 more source

Improving reference standards for validation of AI-based radiography. [PDF]

Br J Radiol, 2021
Duggan GE, Reicher JJ, Liu Y, Tse D, Shetty S.   +4 more
europepmc   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

A Systematic Review of Evidence, Misinterpretations, and the Urgent Need for Population-Specific Reference Standards Related to Vitamin D Deficiency in India: A Global Myth Imposed Locally? [PDF]

Cureus
Laik JK, Kumar R, Sunder A, Laik AD, Ghosh M, Thakur R, Mishra A.   +6 more
europepmc   +1 more source

Determination of age reference standards based on mandibular third molar root development in a Ugandan population aged 10-22 years. [PDF]

Egypt J Forensic Sci, 2022
Mutebi AK, Kamulegeya A, Nabaggala G, Mwesigwa CL.   +3 more
europepmc   +1 more source