Results 181 to 190 of about 741,842 (292)

Space safety regulations and standards /

, 2010
When international rules and regulations governing space travel were first being developed, only a few countries had any space presence and commercial space activity was non-existent. Today, over 50 countries have on-orbit satellites and commercial space
Jakhu, Ram., Pelton, Joseph N.
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

The ATCC Genome Portal: Microbial Genome Reference Standards with Data Provenance. [PDF]

Microbiol Resour Announc, 2021
Benton B, King S, Greenfield SR, Puthuveetil N, Reese AL, Duncan J, Marlow R, Tabron C, Pierola AE, Yarmosh DA, Combs PF, Riojas MA, Bagnoli J, Jacobs JL.   +13 more
europepmc   +1 more source

Sharon G. Lias

, 2005
SHARON G. LIAS NBS/NIST: 1956-2001 Birth: 16 September 1935, Cherokee, Oklahoma EDUCATION: College of William and Mary, BS (Chemistry), 1957 American University, MS (Physical Chemistry), 1965 American University, PhD (Physical Chemistry), 1972 ...
National Institute of Standards and Technology
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Bioelectrical impedance vector analysis in older adults: reference standards from a cross-sectional study. [PDF]

Front Nutr
Campa F, Annunziata G, Barrea L, Sampieri A, Ceolin C, De Rui M, Sguaizer F, Petri C, Spataro F, Mascherini G, Cremasco MM, Sergi G, Moro T, Paoli A.   +13 more
europepmc   +1 more source

Effects of Expert-Determined Reference Standards in Evaluating the Diagnostic Performance of a Deep Learning Model: A Malignant Lung Nodule Detection Task on Chest Radiographs. [PDF]

Korean J Radiol, 2023
Huh JE, Lee JH, Hwang EJ, Park CM.
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Correction: Bioelectrical impedance vector analysis in older adults: reference standards from a cross-sectional study. [PDF]

Front Nutr
Campa F, Annunziata G, Barrea L, Sampieri A, Ceolin C, De Rui M, Sguaizer F, Petri C, Spataro F, Mascherini G, Cremasco MM, Sergi G, Moro T, Paoli A.   +13 more
europepmc   +1 more source

Primary Quantitative Reference Standards for Viral Nucleic Acids Should Be Developed Using Digital Polymerase Chain Reaction Instead of Consensus Testing. [PDF]

J Clin Microbiol, 2023
Hayden RT.
europepmc   +1 more source