Results 91 to 100 of about 30,058,457 (307)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
A SPECIAL CONTROL SYSTEM FOR CONTROLLING THE POSITION OF THE PATH IN THE PLAN
Nauka ta progres transportu, 2008 The special bench mark system for increasing the accuracy of survey of railway track plan is examined.
I. P. Korzhenevych
doaj
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
State of knowledge of earthworm communities in German soils as a basis for biological soil quality
Soil OrganismsWithin a project aiming to improve the preconditions for the protection of the habitat function of soils in Germany, the database Bo-Info was established, in which soil-biological data from permanent soil monitoring sites of several German states as ...
Stephan Jänsch +8 more
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BMC Public HealthBackground The consequences of trace element exposure on cognitive function in elderly adults have been recognized as primarily attributed to the inflammatory response. It is noteworthy that diet can either exacerbate or reduce the inflammatory response.
Chunlan Tang, Min Shen, Hang Hong
doaj +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Orphanet Journal of Rare DiseasesBackground Myasthenia gravis (MG) is a rare autoimmune disorder. Several new treatment concepts have emerged in recent years, but access to these treatments varies due to differing national reimbursement regulations, leading to disparities across Europe.
Abderhmane Slioui +21 more
doaj +1 more source
Siriraj's Oxygen System : Document for Reference and Maintenance
Siriraj Medical Journal, 2020 This cross-sectional study was done during January to March 1999 by anesthesiologists, engineers and technicians to investigate the whole oxygen system in Siriraj hospital.
Preecha Soontranan, Pradit Somprakit
doaj