Results 91 to 100 of about 28,920,622 (304)
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Time and Length Scales of the Martian Atmospheric Turbulence as Observed by the InSight Lander
Geophysical Research LettersWe provide a statistical analysis of the Martian near‐surface atmospheric turbulence based on in situ wind observations from NASA's InSight lander. We focus on the variations in length and time scales of the Martian atmospheric turbulence caused by the ...
Orkun Temel, Ozgur Karatekin
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Proteomics Analysis of Duck Lung Tissues in Response to Highly Pathogenic Avian Influenza Virus
MicroorganismsDomestic ducks (Anas platyrhynchos domesticus) are resistant to most of the highly pathogenic avian influenza virus (HPAIV) infections. In this study, we characterized the lung proteome and phosphoproteome of ducks infected with the HPAI H5N1 virus (A ...
Periyasamy Vijayakumar +7 more
doaj +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
The Planetary Science JournalThe outer solar system beyond Saturn remains unexplored by dedicated orbital missions. With a launch window opening in 2029, the Uranus Orbiter and Probe (UOP) mission has been prioritized as a NASA Flagship mission for the next decade (2023–2032) to ...
Valerio Filice +6 more
doaj +1 more source
Model Reference Adaptive Control Systems: Background and Development
Measurement + Control, 1977 Of the many classes of adaptive control systems described in the literature this article is primarily concerned with the background and development of the model reference type.
M. L. Tatnall
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
External Disturbances Rejection for Vector Field Sensors in Attitude and Heading Reference Systems. [PDF]
Micromachines (Basel), 2020 Wang Y, Li Z, Li X.
europepmc +1 more source