Results 141 to 150 of about 5,777,999 (339)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

A Functional Software Reference Architecture for LLM-Integrated Systems [PDF]

open access: green
Alessio Bucaioni   +4 more
openalex   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

On adaptive resilient secondary control for DC microgrids under false data injection attacks

open access: yesIET Renewable Power Generation
Distributed cooperative control strategies for DC microgrids have been rapidly evolving in recent years. However, introducing a cyber layer to enhance robustness, scalability, and reliability also exposes the system to potential cyber‐attacks. The damage
Shahab Tawan   +3 more
doaj   +1 more source

Effects of Prism Adaptation on Reference Systems for Extrapersonal Space in Neglect Patients. [PDF]

open access: yesBrain Sci, 2019
Abbruzzese L   +4 more
europepmc   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Design of natural-language interfaces for reference systems

open access: yesInformatika, 2019
The description of the technology of modern natural language interfaces for intelligent systems and language interfaces for question-answering intelligent systems is presented, as well as methods and principles for their design.
Yu. S. Hetsevich   +4 more
doaj  

Comparison of reference systems in the assessment of age-related serum immunoglobulin levels in pediatric patients [PDF]

open access: yesTurk J Med Sci, 2019
Külhaş Çelik İ   +6 more
europepmc   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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