Results 221 to 230 of about 5,777,999 (339)

Performance Assessment of Portable SLAM-Based Systems for 3D Documentation of Historic Built Heritage. [PDF]

Sensors (Basel)
Bonora V, Colapietro M.
europepmc   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Commissioning of a combined stereoscopic x-ray and surface guided radiotherapy system for performing breath hold gated lung radiotherapy. [PDF]

J Appl Clin Med Phys
Baltz GC, Kirsner SM.
europepmc   +1 more source

Splanchnic organ homeostasis in experimental endotoxin shock : with special reference to the endothelin and renin-angiotensin systems

, 1999
Anders Oldner
openalex  

Underwater Communication and Position Reference System - OC2020 A-034

, 2020
Biao Su, Eleni Kelasidi, Eirik Storås Thorbjørnsen   +2 more
openalex   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Correction: Evaluation of the dietitians adherence to nutrition support guidelines or protocols in Saudi hospitals and identifications of the barriers to compliance. [PDF]

Front Nutr
Zaher S, Alhussaini AS, Abdulghani RZ, Azzouni RE, Aalouh SK, Alharbi SM, Albukhari S.   +6 more
europepmc   +1 more source

Overweight and Obesity Based on Four Reference Systems in 18,382 Paediatric Patients with Type 1 Diabetes from Germany and Austria. [PDF]

J Diabetes Res, 2015
Flechtner-Mors M, Schwab KO, Fröhlich-Reiterer EE, Kapellen TM, Meissner T, Rosenbauer J, Stachow R, Holl RW.   +7 more
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Wavelength Dependence of fs Laser Ablation Ionisation Mass Spectrometry: a Dedicated Study on NIST SRM 664. [PDF]

Rapid Commun Mass Spectrom
Grimaudo V, Riedo A, Tulej M, Wurz P.
europepmc   +1 more source