Results 131 to 140 of about 20,448,734 (385)

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

FEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp, Katharina Rataj, Stefanie König, Marcia E. Newcomer, Oliver Werz, Ulrike Garscha   +5 more
wiley   +1 more source

New Reference Values for Calcium [PDF]

Annals of Nutrition and Metabolism, 2013
The nutrition societies of Germany, Austria and Switzerland are the joint editors of the ‘reference values for nutrient intake'. They have revised the reference values for the intake of calcium and published them in June 2013. The reference values for the calcium intake for infants are derived from the calcium content of breast milk. For infants from 4
openaire   +3 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

FEBS Letters, EarlyView.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche, John R. Riordan, Burkhard Tümmler   +2 more
wiley   +1 more source

Reference values for spirometry in Brazilian children [PDF]

Jornal Brasileiro de Pneumologia
Objective: To generate reference values for spirometry in Brazilian children 3-12 years of age and to compare those values with the values employed in the equations currently in use in Brazil. Methods: This study involved healthy children, 3-12 years of
Marcus Herbert Jones, Paula Cristina Vasconcellos Vidal, Fernanda Cordoba Lanza, Danielle Corrêa França de Melo Franco Silva, Paulo Márcio Pitrez, Ana Paula Bigliardi de Freitas Olmedo, Edjane Figueiredo Burity, Kennedy Long Schisler, Leonardo Araújo Pinto, Aline Dill Winck, Edna Lúcia Santos de Souza, Anick Augustin Oliveira, Maria Ângela Gonçalves de Oliveira Ribeiro, Lidia Alice Gomes Monteiro Marin Torres, Maria de Fátima Bazhuni Pombo March   +14 more
doaj   +3 more sources

The Nutritive Value of Fats, with Special Reference to Butter and Margarine [PDF]

, 1948
James Smith
openalex   +1 more source

Reference values of spirometry for Finnish adults

Clinical Physiology and Functional Imaging, 2016
Diagnostic assessment of lung function necessitates up‐to‐date reference values. The aim of this study was to estimate reference values for spirometry for the Finnish population between 18 and 80 years and to compare them with the existing Finnish ...
A. Kainu, K. Timonen, J. Toikka, B. Qaiser, J. Pitkäniemi, J. Kotaniemi, A. Lindqvist, E. Vanninen, E. Länsimies, A. Sovijärvi   +9 more
semanticscholar   +1 more source

A coiled‐coil domain triggers oligomerization of MmpL10, the mycobacterial transporter of trehalose polyphleate precursor

FEBS Letters, EarlyView.
Most MmpLs transport lipids and glycolipids of the complex mycomembrane of mycobacteria. This study shows that MmpL10 from Mycobacterium smegmatis, the transporter of the trehalose polyphosphate precursor, harbors a coiled‐coil‐like extension. Biochemical and electron microscopy studies demonstrate that the coiled‐coil enables MmpL10 to trimerize.
Julie Couston, Jérôme Feuillard, Aurélie Ancelin, Joséphine Lai‐Kee‐Him, Konstantin Brodolin, Christian Chalut, Pontus Gourdon, Mickaël Blaise   +7 more
wiley   +1 more source

Reference values for methacholine reactivity (SAPALDIA study)

Respiratory Research, 2005
Background The distribution of airway responsiveness in a general population of non-smokers without respiratory symptoms has not been established, limiting its use in clinical and epidemiological practice.
Perruchoud André, Brändli Otto, Zellweger Jean-Pierre, Künzli Nino, Schindler Christian, Jayet Pierre-Yves, Keller Roland, Schwartz Joel, Ackermann-Liebrich Ursula, Leuenberger Philippe   +9 more
doaj   +1 more source

The Prevention of Opium Addiction, with Special Reference to the Value of Galvanism for Relief of Neuralgic Pain [PDF]

, 1885
J. B. Mattison
openalex   +1 more source