Results 201 to 210 of about 7,051,447 (341)

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

Establishing reference values for the pediatric abdominal aorta in MRI. [PDF]

Eur Radiol
Metz C, Pohrt A, Glutig K, Anders MS, Veldhoen S.   +4 more
europepmc   +1 more source

Age-specific reference values for cerebrospinal fluid protein concentrations in children in southern China

, 2019
Zhigang Liu, Deqin Jia, Jieming Dai, Xing Zhou, Zhoulian Qin, Liang Chen, Jieyan Zhang, Guohua Chen, Xiaocheng He, Ruipin Wan, Xingguang Ye   +10 more
openalex   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Reference Values for Permanent-Tooth Emergence in Hungarian Children: A Cross-Sectional Study. [PDF]

Dent J (Basel)
Kapusi-Papp Z, Máth J, Nemes JÁ.
europepmc   +1 more source

Development of reference values and equations for the pulmonary function of Nigerian children aged 6–11 years measured with digital peak flow meter and its validation against local and the Global Lung Function Initiative (GLI) equations

Peter Odion Ubuane, Olufunke Adewumi Ajiboye, Ayodeji Olushola Akinola, Motunrayo Oluwabukola Adekunle, Gbenga Akinyosoye, Omotola Aderiyike Ajayi, Mogbafolu Olugbemiga Kayode‐Awe, Chidimma Imma Ohagwu, Olatunde Adegboyega Odusote, Barakat Adeola Animasahun, Fidelis Olisamedua Njokanma   +10 more
openalex   +1 more source

Establishing Reference Values for Thyroid Vascularity Using Ultra-Micro Angiography (UMA) Ultrasound Technology [PDF]

Luciana Moisa-Luca, Andreea Borlea, Stefania Alexandra BUNCEANU, Dana Stoian   +3 more
openalex   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Age-Specific Biometric Ratios of the Posterior Fossa in Pediatric Neuroimaging: Establishing Normative Reference Values. [PDF]

Iran J Child Neurol
Mirfendereski S, Fesharaki S, Zadehmir M.   +2 more
europepmc   +1 more source

Blood Pressure Reference Values in Infants Under 1 Year of Age. Oscillometric and Auscultatory Parameters [PDF]

Enrique Blanca Jover, Andrea Villanueva‐Garcia, Francisco Contreras‐Chova, Antonio Jeréz-Calero, Jose Uberos‐Fernandez   +4 more
openalex   +1 more source