Molecular cancer prevention: Intercepting disease
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Differences in severity grading of lung hyperinflation using GLI <i>versus</i> ECSC reference values. [PDF]
Wahab L +4 more
europepmc +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
Reference Values for the Haemophilia Joint Health Score in Patients With Severe Haemophilia Derived From the Canadian Bleeding Disorder Registry. [PDF]
Nguyen KT +5 more
europepmc +1 more source
Reference values of spherical equivalent for predicting the onset and progression of myopia among children and adolescents in China. [PDF]
Qin R +10 more
europepmc +1 more source
Application of Gas Chromatographic Retention Indices to GC and GC-MS Identification with Variable Limits for Deviations Between Their Experimental and Reference Values. [PDF]
Zenkevich IG.
europepmc +1 more source
Reference Values for Macronutrients in Human Milk: the Mothers, Infants and Lactation Quality (MILQ) Study. [PDF]
Lewis JI +14 more
europepmc +1 more source
openaire +1 more source

