Results 141 to 150 of about 8,013 (292)
Experiment: Referential last names contribute a non-at-issue inference about family membership
This project contains the material related to an experiment testing the issueness status of the family membership inference contributed by referential uses of last ...
Julien Foglietti
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Nonattributive and nonreferential uses of definite descriptions
This paper revisits Donnellan’s distinction between referential and attributive uses of definite descriptions and argues that it is not exhaustive. Donnellan characterizes the distinction in terms of two criteria: the speaker’s intentions and the type of
Matuszkiewicz, Maria
core +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Attraction Effects in Referential Dependencies
This dissertation explores the differences in the real-time processing of long-distance dependencies and how the processing of these dependencies functions within a cue-based retrieval model.
Graham, Emily
core
PROSES KONSTRUKSI MAKNA DALAM BAHASA JAWA DAN INDONESIA
Litera, 2015 This study aims to describe meaning construction processes in Javanese and Indonesian. It employed cognitive linguistic theories. The data sources were written and spoken languages in newspapers, books on Javanese and Indonesian proverbs, and ...
Deli Nirmala
doaj
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Permutation map self-referential control generator
This paper proposes a compact pseudorandom number generator, mint, based on a bit permutation map with self-referential control. The generator uses only a minimal internal state and basic integer operations, while introducing nonlinear and partially ...
Hinata Maeda
core