Results 61 to 70 of about 115,014 (304)
Anticholinergic burden and polypharmacy in patients referred from primary care to tertiary dementia centers in Brazil [PDF]
Anticholinergic burden (ACB) and polypharmacy are poorly studied in the context of primary care in Brazil. Objective: To evaluate the ACB and polypharmacy of individuals with suspected dementia referred from primary care to tertiary dementia outpatient ...
Raphael Machado Castilhos +6 more
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Psychology has shown increased involvement in the health care system yet suffers from a lack of knowledge regarding the nature and workings of this system and, conversely, the health care system lacks knowledge about the nature and workings of psychology.
Kalb, Elizabeth
core +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Background/Aims: Headache is the most common new neurological symptom seen by general practitioners and neurologists. This study describes headache consultation, prescription, and referral rates in a large sample of UK general practices.
Ridsdale, L, Gulliford, M, Latinovic, R
core +1 more source
Background To investigate the value of audio-recordings in aiding patient understanding and recall of preoperative breast reconstruction information. Methods This was a prospective cohort study.
Josipa Petric +3 more
doaj +1 more source
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
Assessment of the interdisciplinary collaboration between the periodontology and restorative dentistry departments, according to the consultation notes [PDF]
Background: This study aims to evaluate the interdisciplinary consultation patterns between the Departments of Periodontology (DP) and Restorative Dentistry (DR) by retrospectively analyzing structured consultation request forms. The primary objective is
Fehime Alkan Aygor +2 more
doaj +1 more source
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source

