Results 61 to 70 of about 115,014 (304)

Anticholinergic burden and polypharmacy in patients referred from primary care to tertiary dementia centers in Brazil [PDF]

open access: yesDementia & Neuropsychologia
Anticholinergic burden (ACB) and polypharmacy are poorly studied in the context of primary care in Brazil. Objective: To evaluate the ACB and polypharmacy of individuals with suspected dementia referred from primary care to tertiary dementia outpatient ...
Raphael Machado Castilhos   +6 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

What do physicians want?: an examination of physician's use of psychological consultation and referral

open access: yes, 1985
Psychology has shown increased involvement in the health care system yet suffers from a lack of knowledge regarding the nature and workings of this system and, conversely, the health care system lacks knowledge about the nature and workings of psychology.
Kalb, Elizabeth
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Headache and migraine in primary care: consultation, prescription, and referral rates in a large population

open access: yes, 2006
Background/Aims: Headache is the most common new neurological symptom seen by general practitioners and neurologists. This study describes headache consultation, prescription, and referral rates in a large sample of UK general practices.
Ridsdale, L, Gulliford, M, Latinovic, R
core   +1 more source

Improving preoperative breast reconstruction consultations: a qualitative study on the impact of personalised audio-recordings

open access: yesBMC Women's Health, 2021
Background To investigate the value of audio-recordings in aiding patient understanding and recall of preoperative breast reconstruction information. Methods This was a prospective cohort study.
Josipa Petric   +3 more
doaj   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Assessment of the interdisciplinary collaboration between the periodontology and restorative dentistry departments, according to the consultation notes [PDF]

open access: yesJournal of Oral Health and Oral Epidemiology
Background: This study aims to evaluate the interdisciplinary consultation patterns between the Departments of Periodontology (DP) and Restorative Dentistry (DR) by retrospectively analyzing structured consultation request forms. The primary objective is
Fehime Alkan Aygor   +2 more
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

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