Results 61 to 70 of about 2,382 (289)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Distributed refinement algorithm for WSN localization
Tongxin xuebao, 2015 A distributed refinement algorithm was proposed based on the error analyzing of range-based WSN localization.In each iteration,the proposed algorithm identified “error nodes” and “effective nodes” according to the idea of“magnetic pole”at first; then,it choosed two nodes with the minimum relative deviations in the 1-hop neighbors set of error node,and ...
Ying-biao YAO, Nan-lan JIANG
openaire +2 more sources
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
A refined extreme quantiles estimator for Weibull tail-distributions
, 2022 We address the estimation of extreme quantiles of Weibull tail-distributions. Since such quantiles are asymptotically larger than the sample maximum, their estimation requires extrapolation methods. In the case of Weibull tail-distributions, classical extreme-value estimators are numerically outperformed by estimators dedicated to this set of light ...
Girard, Stéphane, El Methni, Jonathan
openaire +4 more sources
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Exact and Soft Successive Refinement of the Information Bottleneck. [PDF]
Entropy (Basel), 2023 Charvin H, Catenacci Volpi N, Polani D.
europepmc +1 more source