Results 51 to 60 of about 728 (254)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Vector cascade algorithms and refinable function vectors in Sobolev spaces
, 2002 In this paper we shall study vector cascade algorithms and refinable function vectors with a general isotropic dilation matrix in Sobolev spaces. By investigating several properties of the initial function vectors in a vector cascade algorithm, we are ...
Bin Han, Han, Bin
core +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Orthogonality criteria for compactly supported refinable functions and refinable function vectors
, 2008 . A refinable function φ(x) : R n → R or, more generally, a refinable function vector (x) = [φ1(x),...,φr(x)] T is an L 1 solution of a system of (vector-valued) refinement equations involving expansion by a dilation matrix A, which is an expanding ...
Yang Wang +3 more
core
Structure of refinable splines
, 2007 A refinable spline is a compactly supported refinable function that is piecewise polynomial. Refinable splines, such as the well known B-splines, play a key role in computer aided geometric designs.
Wang, Yang +4 more
core +1 more source
A Refined Evaluation Function for the MinLA Problem [PDF]
, 2006 This paper introduces a refined evaluation function, called Φ, for the Minimum Linear Arrangement problem (MinLA). Compared with the classical evaluation function (LA), Φ integrates additional information contained in an arrangement to distinguish arrangements with the same LA value.
Eduardo Rodriguez-Tello +2 more
openaire +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Symmetric multivariate orthogonal refinable functions
, 2004 In this paper, we shall investigate the symmetry property of a multivariate orthogonal M-refinable function with a general dilation matrix M. For an orthogonal M-refinable function ϕ such that ϕ is symmetric about a point (centro-symmetric) and ϕ ...
Han, Bin
core +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source