Results 121 to 130 of about 157,821 (303)
Finite element model based on refined plate theories for laminated glass units
Latin American Journal of Solids and StructuresLaminated glass units exhibit complex response as a result of different mechanical behavior and properties of glass and polymer foil. We aim to develop a finite element model for elastic laminated glass plates based on the refined plate theory by Mau ...
Alena Zemanová +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley +1 more source
SmallTalk: a novel small‐sized fusion tag for peptide expression and purification
FEBS Open Bio, EarlyView.The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq +3 more
wiley +1 more source
The FENET plate/shell fabrication procedural benchmark and 'round robin' exercise [PDF]
, 2005 Plate and shell construction is common across many industrial sectors and covers components and structures that range from the relatively unimportant to safety-critical.
Wood, Jim
core
Naked cuticle is essential for Drosophila wing development beyond Wingless signaling
FEBS Open Bio, EarlyView.Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley +1 more source
FEBS Open Bio, EarlyView.KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli +9 more
wiley +1 more source
Flexure Analysis of Functionally Graded Plates Using {2,2}-Refined Zigzag Theory
Havacılık ve Uzay Teknolojileri Dergisi, 2019 This study investigates the flexure analysis of functionally graded (FG) plates using {2,2}-refined zigzag plate theory which considers transverse normal deformation along the thickness of plates.
Mehmet Dorduncu
doaj
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
STAEBL: Structural tailoring of engine blades, phase 2 [PDF]
The Structural Tailoring of Engine Blades (STAEBL) program was initiated at NASA Lewis Research Center in 1980 to introduce optimal structural tailoring into the design process for aircraft gas turbine engine blades.
Brown, K. W., Hirschbein, M. S.
core +1 more source
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source