Results 151 to 160 of about 297,066 (279)

KNexPHENIX: A PHENIX-Based Workflow for Improving Cryo-EM and Crystallographic Structural Models. [PDF]

J Chem Inf Model
Nandi S, Conn GL.
europepmc   +1 more source

A Multifunctional Mesoporous Janus Separator With Optimized Mass Transport Regulation Enabling 800‐Cycle Lithium‐Oxygen Batteries

Advanced Science, EarlyView.
To resolve the fundamental cycling decay of lithium‐oxygen batteries arising from lithium dendrite propagation, anode corrosion, and cathode passivation, we fabricate a mesoporous silica/polyurethane Janus separator integrating interfacial protection and mass transport modulation, which markedly enhances battery cycling stability and cycle life ...
Hailiang Mu, Anlong Liu, Kun Luo, Yaming Pang, Chengde Xie, Xiaoteng Liu, Zhihong Luo, Guangbin Zhu, Yucheng Wang, Qirong Liu, Yongbing Tang   +10 more
wiley   +1 more source

Combining AI Structure Prediction and Integrative Modeling for Nanobody-Antigen Complexes. [PDF]

J Chem Inf Model
Sánchez-Marín M, Giulini M, Bonvin AMJJ.   +2 more
europepmc   +1 more source

TGFBI Maintains Fibrocartilage Homeostasis by Restraining O‐GlcNAcylation to Inactivate and Destabilize ADAMTS16 in Temporomandibular Joint Osteoarthritis

Advanced Science, EarlyView.
TGFBI deficiency elevates O‐GlcNAcylation, promoting the transcriptional activation of ADAMTS16 and OGT‐mediated post‐translational modification of ADAMTS16 at Ser1170. This leads to its stabilization and accumulation, driving chondrocyte metabolic disorders and senescent phenotypes, ultimately resulting in fibrocartilage dysfunction and TMJOA ...
Xin Liu, Xinyue Luo, Jie Zhao, Ziyan Jiang, Jiayi Zhai, Taomin Zhu, Xueke Jia, Xiaohan Ma, Henghua Jiang, Huimin Li, Yaping Feng, Jin Ke, Xing Long   +12 more
wiley   +1 more source

NMR Structural Elucidation of Mitoxantrone-Gonadotropin-Releasing Hormone (GnRH) Conjugates Implicated in Hormone-Dependent Cancer. [PDF]

Int J Mol Sci
Biniari G, Tzoupis H, Javornik U, Georgiou N, Liapakis G, Mavromoustakos T, Tselios T, Simal C.   +7 more
europepmc   +1 more source

High-resolution Structure Refinement

, 2008
The `small-molecule' program SHELXL is finding increased application in refinement of macromolecules against high resolution data. SHELXL is slow (compared with other macromolecular programs) but very general.
George M. Sheldrick
core  

Chronic Stress Promotes Gastric Cancer Metastasis by Inducing Microbiota‐Associated Kynurenine Accumulation and Macrophage Remodeling

Advanced Science, EarlyView.
Chronic stress reshapes the gut microbiota and enriches Lactobacillus reuteri, promoting microbiota‐associated kynurenine accumulation through altered tryptophan metabolism. Kynurenine drives immunosuppressive remodeling of tumor‐associated macrophages through TNFR2–C/EBPβ signaling, thereby enhancing gastric cancer dissemination.
Sicheng Zhao, Zhiyuan Song, Jingcheng Zhang, Jiaheng Lou, Shuo Zhang, Boqiang Liu, Yunhai Wei, Fengmei Qiu, Tao Jiang, Guangji Zhang   +9 more
wiley   +1 more source

Crystal structure of fucoxanthin: resolving a long-standing crystallographic challenge. [PDF]

Acta Crystallogr C Struct Chem
Wakasa Y, Minoura M.
europepmc   +1 more source

Strongly Anisotropic and Rapid Excitons Transport in Organic Crystal

Advanced Science, EarlyView.
The increased exciton diffusion length is beneficial to simplify device design and enhance photoelectric conversion efficiency. But the isotropic exciton diffusion may lead to reduced transport efficiency directed to the charge separation site. Here we have successfully achieved strongly anisotropic and rapid excitons transport in thienopyrrole ...
Minjie Li, Zheng‐Fei Liu, Jiajia Ma, Dayujia Huo, Ganglong Cui, Qing‐Zheng Yang, Yan Wan   +6 more
wiley   +1 more source

Moral Dilemmas Regarding Physical Restraints in Intensive Care Units: Understanding Autonomy, Beneficence, Non-Maleficence and Justice in the Use of Physical Restraints [PDF]

Junya Zhou,1 Qingzhu Qin,1 Songge Chen,1 Hongmei Zhang2 1Department of Cardiology, Henan Provincial Key Medicine Laboratory of Nursing, Henan Provincial People’s Hospital; Zhengzhou University People’s Hospital, Zhengzhou, Henan, 450003, People’s ...
Qin Q, Zhang H, Chen S, Zhou J
core