Results 41 to 50 of about 329,980 (240)

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

open access: yesFEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source

Spin-orbit effects on reflectance anisotropy spectroscopy [54]

open access: yes, 2004
We study the effects of the spin-orbit coupling on the reflectance anisotropy spectroscopy of semiconductor surfaces. A microscopic formulation based on a semi-empirical tight binding approach which includes spin-orbit interaction is used and theoretical
Vazquez-Nava, R.A.   +2 more
core   +1 more source

Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling

open access: yesFEBS Open Bio, EarlyView.
Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt   +2 more
wiley   +1 more source

Multiscale BRDF Modeling and Scale Effect Analysis Using UAV Multiangle Remote Sensing

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Uncrewed aerial vehicles (UAVs) are increasingly used in close-range remote sensing due to flexible multiangle observations and high spatial resolution.
Junqin Xie   +6 more
doaj   +1 more source

Temperature induced changes in the optical properties of skin in vivo

open access: yesScientific Reports, 2021
Knowledge of temperature-induced changes of skin optical properties is required for accurate dosimetry of photothermal treatments. We determined and compared in vivo optical properties of mouse ear skin at different temperatures. The diffuse reflectance,
Tyler W. Iorizzo   +4 more
doaj   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian   +8 more
wiley   +1 more source

A Manual Transportable Instrument Platform for Ground-Based Spectro-Directional Observations (ManTIS) and the Resultant Hyperspectral Field Goniometer System

open access: yesSensors, 2013
This article presents and technically describes a new field spectro-goniometer system for the ground-based characterization of the surface reflectance anisotropy under natural illumination conditions developed at the Alfred Wegener Institute (AWI).
Marcel Buchhorn   +2 more
doaj   +1 more source

Effect of surface BRDF of various land cover types on geostationary observations of tropospheric NO2 [PDF]

open access: yesAtmospheric Measurement Techniques, 2014
We investigated the effect of surface reflectance anisotropy, bidirectional reflectance distribution function (BRDF), on satellite retrievals of tropospheric NO2.
K. Noguchi   +6 more
doaj   +1 more source

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias   +3 more
wiley   +1 more source

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