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How Reflectance Confocal Microscopy Works
2011Reflectance confocal microscopy (RCM) represents a novel approach for the evaluation of the skin enabling the en-face visualization of the epidermis and superficial dermis at a nearly cellular-level resolution. This new diagnostic technique has several advantages because it is performed in vivo, it is a noninvasive, painless procedure that does not ...
Isabel Kolm, Ralph P. Braun
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In vivo Reflectance Confocal Microscopy
Frontiers in Optics 2008/Laser Science XXIV/Plasmonics and Metamaterials/Optical Fabrication and Testing, 2008Reflectance confocal microscopy provides real time, cellular resolution images of in vivo and ex vivo tissues. I will describe the development of these systems and how the properties of tissue influence the optical and overall system design.
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Reflectance confocal microscopy for mucosal diseases.
Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 2015Non-invasive, real-time microscopic imaging using in vivo reflectance confocal microscopy (RCM) has been demonstrated to be a useful tool for the evaluation of skin diseases and in particular for skin neoplasms. Recently, the RCM devices dedicated to the skin have also been applied to perform "virtual biopsies" of the oral, genital and ocular mucosa ...
CINOTTI, ELISA +5 more
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Anal melanosis diagnosed by reflectance confocal microscopy.
The Australasian journal of dermatology, 2014Until now, in vivo reflectance-mode confocal microscopy (IVCM) has been applied only to pigmented lesions of the vulvar and oral mucosa, but not to anal mucosa lesions. We present the first case in which IVCM has been used to diagnose anal melanosis. Clinical and dermoscopic features were of concern while IVCM found the draped pattern already described
CINOTTI, ELISA +5 more
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Evaluation of reflectance confocal microscopy in dermatophytosis
Mycoses, 2012SummaryTraditional diagnostic testing for dermatophyte infection currently requires skin scraping for light microscopy and/or fungal culture or skin biopsy. Immunofluorescent microscopy can also be used with calcofluor stain. All of these tests can be time‐consuming to perform, require a waiting period for results and are invasive.
Dai, Hui, Sun, Xue-cheng, Xu, Ai-e
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In vivo reflectance confocal microscopy.
Cutis, 2018Reflectance confocal microscopy (RCM) has recently received Category I Current Procedural Terminology (CPT) codes by the Centers for Medicare & Medicaid Services for reimbursement comparable to a skin biopsy. In this article, we present a review of RCM imaging and its benefits and limitations in diagnosis and treatment planning.
Amanda, Levine, Orit, Markowitz
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Anetoderma observed with reflectance confocal microscopy
Italian Journal of Dermatology and Venereology, 2020Cinotti, Elisa +5 more
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Reflectance confocal microscopy of cutaneous sarcoidosis
Skin Research and Technology, 2021Gonzalo Segurado‐Miravalles +6 more
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In Vivo Reflectance Confocal Microscopy in Dermatology
2016Imaging techniques capable of noninvasive, high-resolution, skin imaging in vivo have been the focus of recent attention in the dermatology field. These efforts are directed to improve the diagnostic accuracy of skin cancer, especially cutaneous melanoma.
Alarcon I., Longo C., Gonzalez S.
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Reflecting on Confocal Microscopy: A Personal Perspective
2013The first practical laser scanning confocal microscopes were introduced to the biomedical community over 30 years ago. Their subsequent development continues to influence the introduction of new methods and applications of optical sectioning microscopy.
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