Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Design of experiments methodology in studying near-infrared spectral information of model intact tablets : simultaneous determination of metoprolol tartrate and hydrochlorothiazide in solid dosage forms and powder compressibility assessment using near-infrared spectroscopy [PDF]
Near-infrared spectroscopy (NIRS) is applied in pharmaceutical industry for monitoring drug content during tablet manufacturing process. NIRS method, once developed and validated, is used over years and it is of critical importance to insure method ...
Vranic, Branko Z.
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Nanostructured zinc aluminates: A promising material for cool roof coating
Nanostructured zinc aluminate pigments were synthesized using a citrate sol–gel method. All the samples were annealed at 600 °C, 700 °C, 800 °C, and 1100 °C for 6 h, respectively.
S. Sameera +3 more
doaj +1 more source
Mineral composition can be determined using different methods such as reflectance spectroscopy and X-ray diffraction (XRD). However, in some cases, the composition of mineral maps obtained from reflectance spectroscopy with XRD shows inconsistencies in ...
Fardad Maghsoudi Moud +4 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Time domain laser reflectance spectroscopy (TRS) was applied for the first time to evaluate internal fruit quality. This technique, known in medicine-related knowledge areas, has not been used before in agricultural or food research.
Torricelli, Alessandro +13 more
core +1 more source
A note on prediction of maize stover quality by near-infrared reflectance spectroscopy (NIRS) technique [PDF]
Near-infrared reflectance spectroscopy (NIRS) technique was investigated as a means of predicting quality parameters in semi-exotic maize stover.
Plaixats, Josefina +5 more
core +1 more source
Biophysical approaches for studying viral entry
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Polarized Infrared Reflectance Studies for Wurtzite In0.10Ga0.90N Epilayer on Sapphire Grown by MBE
Polarized infrared (IR) reflectance studies of In0.10Ga0.90N epilayer on sapphire substrate (Al2O3) grown by molecular beam expitaxy are presented. The features of the polarized IR reflectance spectra and the optical characteristics of In0.1Ga0.90N were ...
A.I. Aljameel, H.Abu Hassan, S.S. Ng
doaj +1 more source

