Results 51 to 60 of about 1,522,136 (251)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Mineral Interpretation Discrepancies Identified between Infrared Reflectance Spectra and X-ray Diffractograms

Sensors, 2021
Mineral composition can be determined using different methods such as reflectance spectroscopy and X-ray diffraction (XRD). However, in some cases, the composition of mineral maps obtained from reflectance spectroscopy with XRD shows inconsistencies in ...
Fardad Maghsoudi Moud, Fiorenza Deon, Mark van der Meijde, Frank van Ruitenbeek, Rob Hewson   +4 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Leaf-inspired ZnO-Cr2O3/epoxy coatings with tailored visible–NIR reflectance for spectral camouflage applications

Next Materials
The difference in spectral response between the target and the background is very crucial to avoid target detection by surveillance systems in the visible (VIS) and near-infrared (NIR) spectral regions.
Ansa Khan, Muhammad Umar Farooq, Muhammad Abdullah, Muhammad Atiq ur Rehman, Muhammad Rashid, Gohar ali, Muhammad Abdul Basit   +6 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Near-Infrared Spectroscopy for Growth Estimation of Spirulina platensis Cultures

Methods and Protocols
The present study proposes the use of Near-Infrared (NIR) spectroscopy as a rapid method for estimating the growth of Spirulina platensis cultures, avoiding any sample manipulation or pretreatment. NIR spectroscopy in diffuse reflectance mode was used on
Lamprini Malletzidou, Eleni Kyratzopoulou, Nikoletta Kyzaki, Evangelos Nerantzis, Nikolaos A. Kazakis   +4 more
doaj   +1 more source

Polarized Infrared Reflectance Studies for Wurtzite In0.10Ga0.90N Epilayer on Sapphire Grown by MBE

International Journal of Electrochemical Science, 2014
Polarized infrared (IR) reflectance studies of In0.10Ga0.90N epilayer on sapphire substrate (Al2O3) grown by molecular beam expitaxy are presented. The features of the polarized IR reflectance spectra and the optical characteristics of In0.1Ga0.90N were ...
A.I. Aljameel, H.Abu Hassan, S.S. Ng
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Diffuse reflectance mid-infrared spectroscopy is viable without fine milling

Soil Security, 2023
While diffuse reflectance Fourier transform mid-infrared spectroscopy (mid-DRIFTS) has been established as a viable low-cost surrogate for traditional soil analyses, the assumed need for fine milling of soil samples prior to analysis is constraining the ...
Jonathan Sanderman, Colleen Smith, José Lucas Safanelli, Cristine L.S. Morgan, Jason Ackerson, Nathaniel Looker, Cara Mathers, Rebecca Keating, Ashok A. Kumar   +8 more
doaj   +1 more source