Results 71 to 80 of about 79,911 (310)

Scaling spectroscopic approaches – from leaf albedo to ecosystems mapping [PDF]

, 2010
Field based spectroscopy for ecological and environmental monitoring has become an indispensable part of complete observational systems as defined in GEOSS (Global Earth Observation System of Systems).
Malenovský, Z, Bartholomeus, H, Schaepman, M.E., Malenovsky, Z., Schaepman-Strub, G, Schaepman, Michael E; https://orcid.org/, Bartholomeus, H., Hueni, A., Schaepman-Strub, G., Kneubühler, M; https://orcid.org/, Damm, A; https://orcid.org/, Kneubühler, M., Damm, A.   +12 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Notes and Reflections on Impedance Spectroscopy

Pharmaceutica Analytica Acta, 2017
Fil: Frechero, Marisa Alejandra. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Conicet - Bahia Blanca. Instituto de Quimica del Sur. Universidad Nacional del Sur. Departamento de Quimica.
openaire   +2 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Rapid measurement of polycyclic aromatic hydrocarbon contamination in soils by visible and near-infrared spectroscopy [PDF]

, 2013
Polycyclic aromatic hydrocarbons (PAHs) are widely distributed organic pollutants. At petroleum contaminated sites, PAHs are often the key risk drivers because of their carcinogenicity. Assessing the risk of PAH at contaminated sites by conventional soil
Okparanma, Reuben N.
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Effects of Atmospheric, Topographic, and BRDF Correction on Imaging Spectroscopy-Derived Data Products

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Surface reflectance is an important data product in imaging spectroscopy for obtaining surface information. The complex retrieval of surface reflectance, however, critically relies on accurate knowledge of atmospheric absorption and scattering, and the ...
Marius Vogtli, Daniel Schlapfer, Meredith C. Schuman, Michael E. Schaepman, Mathias Kneubuhler, Alexander Damm   +5 more
doaj   +1 more source

Materiais SiO2-TiO2 para a degradação fotocatalítica de diuron

Química Nova, 2011
SiO2-TiO2 materials prepared by sol-gel method were evaluated in the photocatalytic degradation of diuron. The materials were prepared with and without surfactant cetyltrimethylammonium chloride at different temperatures (25, 50 and 100 ºC).
Arthur Alaím Bernardes, Maria Carolina S. Bulhosa, Fábio Ferreira Gonçalves, Marcelo G. Montes D'Oca, Silvana I. Wolke, João Henrique Z. dos Santos   +5 more
doaj   +1 more source

Detection of internal quality in kiwi with time-domain diffuse reflectance spectroscopy

, 2004
Time-domain diffuse reflectance spectroscopy (TRS), a medical sensing technique, was used to evaluate internal kiwi fruit quality. The application of this pulsed laser spectroscopic technique was studied as a new, possible non-destructive, method to ...
Torricelli, Alessandro, M. Ruiz Altisent, Valero Ubierna, Constantino, C. Valero, Pifferi, Antonio, D. S. Johnson, C. J. Dover, Cubeddu, Rinaldo, Valentini, Gianluca, Dover, Colin, PIFFERI, ANTONIO GIOVANNI, Taroni, Paola, Johnson, David, Ruiz-Altisent, Margarita   +13 more
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source