CypD Dependent mPTP Opening Is Crucial for Oxidized Mitochondrial DNA Release in Ferroptosis
Advanced Science, EarlyView.Ferroptosis is driven by mitochondrial permeability transition pore (mPTP) opening, which induces mitochondrial swelling and releases oxidized mitochondrial DNA. The released mtDNA activates cGAS–STING signaling, promotes ferritinophagy, and amplifies ferroptotic cell death. Disruption of mtDNA repair sensitizes tumors to ferroptosis in vivo, revealing
Hong Zhou +5 more
wiley +1 more source
Research into the Failure Mechanism and Reliability of an Active Frequency-Selective Surface in Complex Environments. [PDF]
Materials (Basel)Wei Z, Suo B, Zhou C, Li Y, Zhang F.
europepmc +1 more source
Astrocyte Enrichment of 3D Cortical Constructs Enhances Brain Repair
Advanced Science, EarlyView.This study highlights the role of astrocytes in supporting neural progenitor cell survival and differentiation after traumatic brain injury. Astrocytes enhanced neuronal differentiation, improved cell survival in co‐cultures, and promoted integration of microfluidics‐based implants with host tissue following implantation. Additionally, increased axonal
Elisa M. Cruz +20 more
wiley +1 more source
High-Performance Optically Transparent EMI Shielding Sandwich Structures Based on Irregular Aluminum Meshes: Modeling and Experiment. [PDF]
Materials (Basel)Voronin AS +9 more
europepmc +1 more source
Advanced Science, EarlyView.This study revealed how the osteoblastic microenvironment determines the fate of cancer cells disseminated in bone, with a focus on whether they colonize, reside in quiescence, or reactivate from dormancy. Targeting integrin signaling may offer promising strategies for preventing quiescent cancer cells reactivation and bone colonization.
Hong‐Li Wang +7 more
wiley +1 more source
Pollutants Transformation During the Regeneration Process of Fluid Catalytic Cracking Catalysts. [PDF]
Angew Chem Int Ed EnglBian J +8 more
europepmc +1 more source
A Mussel‐Inspired Bioadhesive Patch to Selectively Kill Glioblastoma Cells
Advanced Science, EarlyView.An innovative mussel‐inspired bioadhesive patch has been developed for post‐surgical glioblastoma treatment. The patch, which adheres strongly in biological environments, releases a localized treatment. This treatment, acting via reactive oxygen species, shows specific toxicity to glioblastoma cells.
Jose Bolaños‐Cardet +5 more
wiley +1 more source
From Qualitative Localisation to Quantitative Verification: Integrating Active IR Thermography and Laser Scanning in Wind Turbine Blade Inspection. [PDF]
Materials (Basel)Stawiarski A.
europepmc +1 more source
Advanced Science, EarlyView.Lithium‐epigallocatechin gallate nanoparticles (Li‐EGCG NPs) are co‐transplanted with embryonic stem cell‐derived retinal ganglion cells (ESC‐RGCs) to enhance cell survival and therapeutic efficacy in an acute pathological glaucomatous injury model. This synergistic approach protects RGC cells, preserves retinal structure and improves visual function ...
Moxin Chen +14 more
wiley +1 more source