Results 71 to 80 of about 33,060 (306)

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang   +10 more
wiley   +1 more source

Evaluation of anti-reflective crack resistance based on the UFAC stress-absorbing layer

open access: yes河南理工大学学报. 自然科学版
ObjectivesTo address the issue of reflective cracking in “white and black” pavement technology, this paper proposes an optimized design for a skeleton-dense UFAC stress-absorbing layer.
LI Zhi, TONG Jing
doaj   +1 more source

Evidence of Iron Accumulation in Cerebral Adrenoleukodystrophy: A Potential Novel Disease Mechanism

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT In this first application of Quantitative Susceptibility Mapping Source Separation to cerebral adrenoleukodystrophy, we uncovered alterations in iron and myelin within lesions and normal appearing white matter. As validation, we demonstrate abnormal iron accumulation in those same compartments within primary brain tissue.
Christina L. Nemeth   +8 more
wiley   +1 more source

Fracture characteristics of asphalt mixtures containing asphalt millings with geosynthetic fragments [PDF]

open access: yesE3S Web of Conferences
The increasing cost of asphalt and environmental concerns have created a greater interest in exploring the possibility of incorporating higher percentages of reclaimed asphalt pavement (RAP) materials in asphalt mixtures.
Saxena Ashray   +2 more
doaj   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling   +16 more
wiley   +1 more source

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich   +19 more
wiley   +1 more source

Evaluation of Interlayer Reinforcement Effectiveness in Road Pavement Rehabilitation Using FEM Modeling and Fracture Mechanics Analysis

open access: yesBuildings
In this paper, the effectiveness of reinforcements for flexible pavements is evaluated through an analysis of reflective cracking. Different stiffness and thickness reinforcements are considered for the rehabilitation of an already cracked pavement.
Arianna Antoniazzi   +4 more
doaj   +1 more source

Green Up Pavement Rehabilitation Design Tool [PDF]

open access: yes, 2019
While designers produce pavement rehabilitation recommendations every day, for projects of all sizes, most designers have little information on the environmental impact of their recommendations.
Andrei, Dragos   +2 more
core   +1 more source

Persistent Bilateral [18F]THK5351 and Migrating Unilateral [18F]FDG Uptake in Anti‐LGI1 Encephalitis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Anti–leucine‐rich glioma‐inactivated 1 encephalitis (LGI1‐E) can cause persistent cognitive deficits, but the mechanisms remain unclear. A 40‐year‐old woman with LGI1‐E presented with subacute cognitive deficits and showed mild left medial temporal lobe (MTL) swelling and fluid‐attenuated inversion recovery (FLAIR) hyperintensity on initial ...
Yusuke Akitomi   +8 more
wiley   +1 more source

Orchard Floor Management Affects Tree Functionality, Productivity and Water Consumption of a Late Ripening Peach Orchard under Semi-Arid Conditions

open access: yesApplied Sciences, 2020
Semi-arid conditions are favorable for the cultivation of late ripening peach cultivars; however, seasonal water scarcity and reduction in soil biological fertility, heightened by improper soil management, are jeopardizing this important sector.
Pasquale Losciale   +4 more
doaj   +1 more source

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