Results 81 to 90 of about 885,510 (305)
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Use of an e‑portfolio mapping tool: connecting experiences, analysis and action by learners
Perspectives on Medical Education, 2019 Reflective practice is an important characteristic of a knowledgeable health professional. Reflection is needed to maintain professional competence, practice-based learning, and an improvement focused attitude.
Sylvia Heeneman +3 more
doaj +1 more source
Using evidence to improve Psychological Therapies Services [PDF]
, 2005 Psychological therapy services offer help to clients with many different sorts of mental health problems using a variety of therapies provided by a range of different professional groups and are supported by a large amount of research evidence.
Iveson, Steve +2 more
core +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Spinning the lens on physician power: narratives of humanism and healing
Perspectives on Medical Education, 2019 Divisive, disabling and dangerous power has featured heavily in health professions literature, social media and medical education. Negative accounts of the wielding of power have discoloured the lens through which the public sees medicine and distorted ...
Mercedes Chan, Laura Nimmon
doaj +1 more source
Diagnostic errors and reflective practice in medicine [PDF]
, 2007 Background: Adverse effects of medical errors have received increasing attention. Diagnostic errors account for a substantial fraction of all medical errors, and strategies for their prevention have been explored. A crucial requirement for that is better
Mamede, S. (Silvia) +2 more
core +3 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Corpus-Based Reflective Practice to Support Chatroom Teaching Practice
Education SciencesTeaching practice has long been considered a fundamental and integral part of any teacher education programme, but also very demanding for novice teachers when they are confronted with the reality of the classroom, for the first time in many cases ...
Elaine Riordan +3 more
doaj +1 more source
NAVIGATING THE ETHICAL LANDSCAPE OF RESEARCH [PDF]
Social Sciences and Education Research ReviewResearch ethics is a critical component of any academic or scientific discipline. The ethical dilemmas that arise in research can be complex and require researchers to consider multiple perspectives and theories.
Abraham Motlhabane
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source