Results 91 to 100 of about 17,387 (307)

GPR124 Alleviates Blood–Brain Barrier Disruption by Enhancing Microvascular Endothelial Function after Traumatic Brain Injury

Advanced Science, EarlyView.
Our study reveals the protective role of GPR124 in maintaining BBB integrity and promoting neurological recovery following TBI. It makes a significant contribution by uncovering a novel molecular interaction between GPR124 and FGFBP1 and linking this to activation of the Wnt/β‐catenin signaling pathway in vascular repair mechanisms.
Chen Wang, Lin Cai, Qiuyuan Gong, Yang Yang, Yuqing Liang, Xinyu Niu, Lai Wei, Ze Liu, Shengju Wu, Yinghui Men, Yaohui Tang, Jun Ding, Hengli Tian, Hao Chen   +13 more
wiley   +1 more source

VIBRATORY STIMULATION OF MUSCLES AND STRETCH REFLEX

The Japanese Journal of Physiology, 1970
1. Firing patterns of Ia afferents and motoneuron efferents were recorded while subjecting homonymous de-efferented triceps surae muscle to vibration applied longitudinally to the tendon.2. The amplitude of vibration (ΔL) necessary to elicit the preferred firing rate of each motoneuron was noted over a wide range (20 to 180cps) of vibration frequencies
HOMMA, Saburo, KOBAYASHI, Hideo, WATANABE, Shiroh   +2 more
openaire   +3 more sources

Normalization reduces the spatial dependency of the jaw-stretch reflex activity in the human masseter muscle

, 2010
The jaw-stretch reflex is the short-latency response in the jaw-closing muscles after a sudden stretch. The hypothesis whether normalization of the jaw-stretch reflex amplitude with respect to prestimulus electromyographic (EMG) activity will make the ...
Naeije, Machiel, Michail Koutris, Arendt-Nielsen, Lars, Kelun Wang, Peter Svensson, Machiel Naeije, Frank Lobbezoo, Lobbezoo, F., Dario Farina, Koutris, Michail, Koutris, M., Wang, K., Farina, Dario, Lars Arendt‐Nielsen, Farina, D., Arendt-Nielsen, L., Svensson, P., Lobbezoo, Frank, Svensson, Peter, Naeije, M., Wang, Kelun   +20 more
core   +1 more source

Dynamic Control of Upper Limb Stretch Reflex in Wrestlers

, 2021
Purpose: The objective of this study was to clarify the characteristics of the upper limb stretch reflex in wrestlers. Methods: Ten wrestlers and 11 control subjects participated in the study. The experiment was divided into two sessions.
Nakagawa, Kento, Crawshaw, Larry, KENTO NAKAGAWA, MISAKI ITEYA, Nakajima, Tsuyoshi, SHO ITO, Iteya, Misaki, Kanosue, Kazuyuki, LARRY CRAWSHAW, Ito, Sho, TSUYOSHI NAKAJIMA, KAZUYUKI KANOSUE   +11 more
core   +1 more source

N, S Co‐Doped Carbon Quantum Dots‐Riboflavin Composite Photosensitizers for Enhanced Iontophoresis‐Assisted Corneal Cross‐Linking

Advanced Science, EarlyView.
This study explores the use of N, S co‐doped carbon quantum dots (NS‐CQDs) as carriers for riboflavin, creating NS‐CQDs‐RF composite photosensitizers. These composites improve riboflavin absorption, enhance ROS generation efficiency, and preserve corneal epithelium integrity.
Tinghong Xu, Yong Liu, Wenjing Zhang, Qiuruo Jiang, Yi Jin, Liangzheng Lin, Lumeng Wang, Zhanhao Gu, Mimi Lin, Shihao Chen   +9 more
wiley   +1 more source

Is the long-latency stretch reflex in human masseter transcortical?

, 2003
The original publication can be found at www.springerlink.comA long-latency stretch reflex (LLSR) has been described in the human masseter muscle, but its pathway remains uncertain.
Nordstrom, M., Pearce, S., Miles, T., Thompson, P.   +3 more
core   +1 more source

GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

Advanced Science, EarlyView.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang, Na Li, Yan Wang, Jing Zhang, Jiahui Liu, Lei Chen, Yongdong Song, Yurong Mu, Yuechen Han, Yafeng Lyu, Xiaofei Li, Hanyue Wang, Jing Wang, Yao Lu, Zhaomin Fan, Daogong Zhang, Haibo Wang   +16 more
wiley   +1 more source

Circular RNA circNrip1 Interacts with SYNCRIP to Promote Neuropathic Pain by Stabilizing Tlr2 mRNA in Primary Sensory Neurons

Advanced Science, EarlyView.
Model of circNrip1 (cNrip1) upregulation driving neuropathic pain mechanisms. After peripheral nerve injury, increased FUS triggers the formation and upregulation of cNrip1 in injured DRG neurons. Upregulated cNrip1 recruits SYNCRIP to the 3′‐UTR of Tlr2 mRNA by binding to both, thereby promoting SYNCRIP‐triggered Tlr2 mRNA stability and increasing ...
Xiaozhou Feng, Jifang Xiao, Congcong Huang, Bao‐Chun Jiang, Bing Wang, Xu Li, Shibin Du, Tolga Berkman, Chun‐Hsien Wen, Weihua Cai, Dilip Sharma, Kun Wang, Longfei Ma, Huijuan Hu, Yuan‐Xiang Tao   +14 more
wiley   +1 more source

Cis‐ and Trans‐Regulatory Factors Independently Shape Phenotypic Heterogeneity of Retinitis Pigmentosa

Advanced Science, EarlyView.
A zebrafish model carrying an identical human RHO S334X allele reveals two independent genetic layers shaping retinitis pigmentosa (RP) severity: a protective 3‐bp cis‐regulatory insertion that attenuates transgene expression, and a dominant trans‐acting modifier that restores a severe phenotype.
Cong Cui, Kotone Nakagawa, Takumi Tateno, Ayaka Dan, Dexin Meng, Yoshihiro Omori, Soma Tomihara, Suzuri Okamoto, Shigeru Sato, Motokazu Tsujikawa   +9 more
wiley   +1 more source

Proposal for Hemiplegic Thumb Rehabilitation Device Based on Repetitive Facilitation Exercise

Machines
In this paper, we propose a thumb rehabilitation device based on the concept of Repetitive Facilitation Exercise (RFE) therapy. Our device only uses rapid passive stretching to the extensor muscle to induce a stretch reflex as a facilitative stimulation.
Koutaro Taniguchi, Yuta Tanda, Yong Yu
doaj   +1 more source