Results 161 to 170 of about 268,124 (290)

GERD (gastroesophageal reflux disease)

open access: diamond, 2010
宮崎 達也   +2 more
openalex   +1 more source

Redox‐Responsive Tellurium‐Bridged Covalent Organic Frameworks/PEG Composites for Targeted Therapy of Diabetic Cardiomyopathy

open access: yesAdvanced Science, EarlyView.
This study unlocks the immense potential of COF@polymer nanocomposites as a multifunctional therapeutic platform for targeted drug delivery in diabetic cardiomyopathy. Abstract Diabetic cardiomyopathy, a major complication of diabetes, is strongly associated with elevated levels of glycated hemoglobin (HbA1c) and reactive oxygen species (ROS). However,
Jing Xue   +13 more
wiley   +1 more source

T1WI‐SWI Dual Modal Magnetic Resonance Nanoprobes for Accurate Diagnosis of Early Stage Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
We developed a smart MRI nanoprobe targeting BACE1 and Aβ plaques. It crosses the blood‐brain barrier. Upon encountering BACE1, the probe is cleaved, enabling T1WI imaging detection. Subsequent reaction with ONOO− induces probe aggregation, enhancing magnetic susceptibility for sensitive SWI imaging of Aβ plaques.
Minghua Li   +13 more
wiley   +1 more source

Unveiling Dipolar Interaction‐Driven Magnetic Field Inhomogeneities in T2 MRI Contrast Agents

open access: yesAdvanced Science, EarlyView.
In this study, chemically designed nanoscale‐distance‐tuned based on silica‐coated iron oxide nanoparticles are used to investigate how dipolar interactions affect magnetic resonance imaging (MRI) contrast. By varying shell thickness, researchers modulated dipolar interactions and observed an exponential increase in transverse relaxivity (r2) that ...
Pelayo García‐Acevedo   +6 more
wiley   +1 more source

Restoration of Occlusal Vertical Dimension in Dental Erosion Caused by Gastroesophageal Reflux: Case Report [PDF]

open access: bronze, 2010
Eduardo Galia Reston   +4 more
openalex   +1 more source

Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors

open access: yesAdvanced Science, EarlyView.
Chen et al. show that the endoplasmic reticulum (ER) stress sensor PERK is downregulated in prefrontal cortex (PFC) astrocytes in major depressive disorder and in chronic‐stress mouse models. In young mice, astrocyte‐specific PERK loss reduces the synaptogenic cue thrombospondin‐1 (TSP1), leading to synaptic and circuit deficits and depressive‐like ...
Kai Chen   +8 more
wiley   +1 more source

Rattan‐Based Solar Evaporator Hits 3.34 Kg·M−2·h−1 and Long‐Term Salt Resistance via Programmed Carbonization

open access: yesAdvanced Science, EarlyView.
A rattan‐based evaporator with bimodal hierarchical porous structures achieves an high evaporation rate of 3.34 kg m−2 h−1 under 1 sun illumination by optimizing the surface water layer, localizing heat, and reducing vaporization enthalpy. Abstract Global water scarcity urgently demands sustainable purification solutions.
Shanshan Jia   +13 more
wiley   +1 more source

Sulfur Vacancy‐Engineered Co9S8‐Ni3S4 Heterostructure as a Hydrogen Spillover Catalyst for Efficient Alkaline Water Splitting

open access: yesAdvanced Science, EarlyView.
A sulfur vacancy‐engineered Co9S8‐Ni3S4 hollow heterostructure is rationally designed to trigger hydrogen spillover, where vacancy‐mediated interfacial modulation enables efficient H migration and accelerates HER kinetics. Abstract Developing highly efficient and robust catalysts based on earth‐abundant materials for electrochemical water splitting ...
Shoushuang Huang   +9 more
wiley   +1 more source

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