Results 251 to 260 of about 398,375 (367)

In vivo toxic and lethal cardiorespiratory effects of a synthetic quaternary ammonium salt derivative of haloperidol in mice

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Hematoxylin–eosin (H&E) stains of the heart, liver, lung, and kidney show acute toxicity. Abstract Background To investigate the toxicity of N‐n‐butyl haloperidol iodide (F2), a quaternary ammonium salt derivative of haloperidol, in mice for potential therapeutic purposes. Methods The acute median lethal dose (LD50) of F2 was determined using the Bliss
Jilin Liao   +6 more
wiley   +1 more source

Imino‐Pyrrole Zn(II) Complexes for the Rapid and Selective Chemical Recycling of Commodity Polymers

open access: yesAngewandte Chemie, EarlyView.
Three imino‐pyrrole zinc (II) catalysts were prepared and applied to the chemical recycling of PLA, PET, and BPA‐PC. Rapid PLA degradation was accomplished in solution and under solvent‐free conditions, the latter giving full conversion at relatively mild temperatures after 11 min.
Jack A. Stewart   +5 more
wiley   +2 more sources

Transplanting neural stem cells overexpressing miRNA‐21 can promote neural recovery after cerebral hemorrhage through the SOX2/LIN28‐let‐7 signaling pathway

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Abstract Background Intracerebral hemorrhage (ICH) remains a devastating neurological disorder with limited therapeutic options. Neural stem cell (NSC)‐based therapies have emerged as a potential regenerative approach, yet the molecular mechanisms regulating NSC behavior require further elucidation.
Wei Dai   +7 more
wiley   +1 more source

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