Results 91 to 100 of about 82,240 (244)

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

open access: yesBritish Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman   +3 more
wiley   +1 more source

International consensus recommendations for identifying malnutrition in children with neurological impairment

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Abstract Children with neurological impairment (CNI) are at increased risk of malnutrition because of functional, medical, and socioeconomic challenges. However, difficulties in obtaining reliable anthropometric measurements and differences in body composition limit the usefulness of conventional nutritional indicators.
Sarah Vermilyea   +19 more
wiley   +1 more source

Reflux Complaints, Symptom Score and the Use of Medication in Patients with Reflux Esophagitis: Results of a Long-Term Follow-Up Study

open access: yesCanadian Journal of Gastroenterology, 2001
Reflux esophagitis requires maintenance treatment. A cross-sectional descriptive study was done to assess the use of medication and prevalence of complaints in patients with esophagitis more than 4.5 years after diagnosis.
Ruud JLF Loffeld
doaj   +1 more source

The state of the mucous membrane of the upper digestive tract in children with combined GERD and chronic gastroduodenal pathology

open access: yesZdorovʹe Rebenka, 2019
Background. The frequency of gastroesophageal reflux disease (GERD) in population is reported to be from 7 to 60 %, and in children it varies from 2–4 to 8.7–49 % according to various authors.
N.V. Kirianchuk
doaj   +1 more source

Bleeding reflux esophagitis: a prospective 1-year study in a university hospital.

open access: yes, 2001
OBJECTIVES: The prevalence of bleeding from reflux esophagitis has not been studied. The aim of the study was to evaluate the 1-yr prevalence of bleeding from reflux esophagitis, as well as the independent factors associated with bleeding.
Cadiot, G   +6 more
core   +1 more source

Mechanisms underpinning the progression of nondysplastic Barrett's oesophagus to cancer

open access: yesThe FEBS Journal, EarlyView.
Barrett's oesophagus confers a low but significant cancer risk. The condition is common but we do not have effective biomarkers to identify susceptible patients. We believe that there is no single factor that determines cancer risk and an understanding of the combinations of interactions (via gene expression and natural selection) between the Barrett's
Yannick H. Derwa   +2 more
wiley   +1 more source

Association of Mean Nocturnal Baseline Impedance and AFS EGJ Grading With AET‐Defined Reflux Burden in Korean Patients

open access: yesJournal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background and Aim Diagnosing gastroesophageal reflux disease (GERD) is challenging in borderline acid exposure time (AET). The Lyon Consensus 2.0 defines AET ≥ 6% as pathological reflux; however, East Asian standards often apply a 4% threshold, creating a diagnostic gray zone.
Ye‐Rin Chae   +9 more
wiley   +1 more source

Medical treatment of gastroesophageal reflux disease

open access: yesThe Turkish Journal of Gastroenterology, 2017
Proton pump inhibitors (PPIs) are the most effective agents in the first-line and maintenance treatment of gastroesophageal reflux disease. As the grade of esophagitis increases, an increase is also observed in the level of endoscopic response to PPIs ...
Serhat Bor, İsmail Hakkı Kalkan
doaj   +1 more source

Toileting Problems and Associated Factors in Adults Enrolled in the Global Angelman Syndrome Registry

open access: yesJournal of Intellectual Disability Research, EarlyView.
ABSTRACT Background Angelman Syndrome (AS) is a rare neurodevelopmental disorder caused by the lack of expression of the UBE3A gene, which can result from abnormalities of the maternally inherited chromosome 15q11‐q13. The purpose of this study is to investigate the most common types of toileting problems in adults with AS and the associated factors of
Emma Walsh   +7 more
wiley   +1 more source

Evaluation of Gastroesophageal Reflux and Gastroesophageal Reflux Disease with Esophageal Endoscopy and Histology in Children [PDF]

open access: yes, 2014
Objectives:The roles of esophageal endoscopy and mucosal biopsy in making diagnoses of gastroesophageal reflux( GER) and gastroesophageal reflux disease( GERD) were retrospectively examined in children.Methods:Thirty-four patients, whose ages ranged from
Fujino, Junko
core  

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