Results 31 to 40 of about 60,557 (267)

Cooperative role of MDSCs and Tregs in alum-induced alloimmune tolerance in corneal transplantation

Scientific Reports
Alum, a widely used adjuvant, has recently been recognized for its capacity to modulate immune responses beyond classical activation. In this study, we investigated whether alum-induced expansion of myeloid-derived suppressor cells (MDSCs) and their ...
Lifang Li, Yuping Han, Xiangrong Xie, Dakun Ren, Ying Zhang, Shaofeng Hao, Xuming Guo   +6 more
doaj   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

The Role of Orthoptists in Refraction

British and Irish Orthoptic Journal
Purpose: In 2022, the General Optical Council initiated a call for evidence concerning the Opticians Act. This consultation aimed to gather input and evidence relevant to potential modifications to the Opticians Act.
Miriam L. Conway, Rakhee Shah, Elizabeth Chapman, Bruce J. W. Evans   +3 more
doaj   +1 more source

Refractive errors [PDF]

Deutsches Ärzteblatt international, 2016
All over the world, refractive errors are among the most frequently occuring treatable distur - bances of visual function. Ametropias have a prevalence of nearly 70% among adults in Germany and are thus of great epidemiologic and socio-economic relevance.In the light of their own clinical experience, the authors review pertinent articles retrieved by a
Ulrich, Schiefer, Christina, Kraus, Peter, Baumbach, Judith, Ungewiß, Ralf, Michels   +4 more
openaire   +2 more sources

Cracking the Code: Which Ocular Symptoms Predict Dry Eye Signs? Insights From a Large International Sicca Registry

Arthritis Care &Research, EarlyView.
Objective The study aimed to identify symptom‐based predictors of dry eye disease (DED) signs in the Sjögren's International Collaborative Clinical Alliance (SICCA) cohort. Methods We performed a retrospective analysis examining 16 ocular symptoms (most graded 0–4) and artificial tear (AT) use (graded 0–3) as predictors of DED signs (abnormal ocular ...
Pragnya R. Donthineni, Chloe Shields, Rohit Muralidhar, Shreya Bhatt, Alan Baer, Robert Fox, Sara S. McCoy, Anat Galor   +7 more
wiley   +1 more source

Corneal Astigmatism After Cataract Surgery: A Review of Mechanisms, Outcomes, and Surgical Considerations

Optics
Background: This narrative review aims to assess multiple strategies available to evaluate and manage corneal astigmatism in the context of cataract surgery, with a focus on the surgical techniques, intraocular lens (IOL) selection, and the integration ...
Andreea-Alexandra-Mihaela Muşat, Cãlin-Petru Tãtaru, Gabriela-Cornelia Muşat, Lucia Bubulac, Mihai-Alexandru Preda, Ovidiu Muşat   +5 more
doaj   +1 more source

Sensitivity of the corneal-plane refractive compensation to change in power and axial position of an intraocular lens

African Vision and Eye Health, 2009
If an intraocular lens is displaced or if its power is changed what are the consequences for the refractive compensation of the eye?  Gaussian optics is used to obtain explicit formulae for the sensitivityof the corneal-plane refractive compensation ...
W. F. Harris
doaj   +1 more source

A Q‐Learning Algorithm to Solve the Two‐Player Zero‐Sum Game Problem for Nonlinear Systems

International Journal of Adaptive Control and Signal Processing, Volume 39, Issue 3, Page 566-581, March 2025.
A Q‐learning algorithm to solve the two‐player zero‐sum game problem for nonlinear systems. ABSTRACT This paper deals with the two‐player zero‐sum game problem, which is a bounded L2$$ {L}_2 $$‐gain robust control problem. Finding an analytical solution to the complex Hamilton‐Jacobi‐Issacs (HJI) equation is a challenging task.
Afreen Islam, Anthony Siming Chen, Guido Herrmann   +2 more
wiley   +1 more source

Comparison of Refractive Outcomes Between Small Lenticule Extraction Using a 500 KHz and a 2 MHz Femtosecond Laser

Diagnostics
Background/Objectives: The aim of this study was to compare the efficacy of correcting myopia and myopic astigmatism between small incision lenticule extraction (SMILE) surgery performed using VisuMax 500 and that using VisuMax 800. Methods: Patients who
Jung Wan Kim, Youngsub Eom, Dong Hyun Kim, Ji Won Jeong, Seh Kwang Park, Jong Suk Song   +5 more
doaj   +1 more source

Variable Stiffness Flexure Structures Enabled by Phase‐Change Gallium and Adhesive Interfacial Locking for Soft Robotic Applications

Advanced Engineering Materials, EarlyView.
A flexure‐based variable stiffness structure is developed by integrating phase‐change modulation and adhesive interfacial locking of gallium. The design enables a wide stiffness variability, transitioning from soft, flexible behavior to rigid, load‐supporting performance.
Sungjin Kim, Sohee John Yoon, Yong‐Lae Park   +2 more
wiley   +1 more source