Results 91 to 100 of about 42,789 (260)
Scientific ReportsDifferences in lenticule shapes may impact on the design of future presbyopic treatments with lenticule surgery. Hence, the objective of this study was to assess the depth of field of eyes after smooth Incision Lenticular Keratomileusis (SILK) surgery ...
Rohit Shetty +6 more
doaj +1 more source
Advanced Science, EarlyView.To accelerate the inverse design of heterostructured metal matrix composites, a closed‐loop scientific machine learning framework integrates continual learning prediction with NSGA‐II‐PMCP optimization. The framework maps microstructural descriptors to strength, toughness, and modulus, expands high‐quality Pareto solutions, and guides experimentally ...
Zhiyan Zhong +11 more
wiley +1 more source
Advanced Science, EarlyView.A graphene oxide nanocarrier presents neuropeptide Y specifically to NPY receptor‐expressing pathways in the amygdala, whose activation selectively suppresses aversive memory formation, without modulating anxiety responses. This circuit‐restricted drug release strategy may impact future design of neuropsychiatric therapies with limited off‐target ...
Elisa Pati +10 more
wiley +1 more source
Multi-Site Study of Patient Reported Vision Quality and Dry Eye Following LASIK
Clinical OphthalmologyMark C Lobanoff,1 Paul M Mann II,2 Mihir Parikh,3 Jason Brenner,4 Brad Hall5 1OVO Lasik and Lens, Saint Louis Park, MN, USA; 2Mann Eye Institute, Houston, TX, USA; 3NVISION Eye Centers, San Diego, CA, USA; 4Boston Vision, Brookline, MA, USA; 5Sengi ...
Lobanoff MC +4 more
doaj
Advanced Science, EarlyView.Single‐cell mechanomics demonstrates that pharmacological perturbation changes cytoskeletal and cortical structure, suppressing cancer cell invasiveness. By integrating atomic force microscopy (AFM)‐based cortical measurements with stimulated emission depletion (STED)‐resolved adhesion and cytoskeletal organization, this approach identifies nanoscale ...
Minhee Ku +4 more
wiley +1 more source
Advanced Science, EarlyView.This study developed an efficacy assessment platform that integrates patient‐derived gastric cancer organoids, atomic force microscopy (AFM)‐based nanomechanical vibration detection, deep learning analysis, and organoid mechanical modeling. It detects picomolar drug effects within 0.1 s signal, achieves 97% classification accuracy, and offers non ...
Ting Zhang +10 more
wiley +1 more source
Outcomes of sclerokeratoplasty in severe ocular surface disease
Scientific ReportsSclerocorneal grafts are procedures considered in cases with extensive corneal and scleral tissue destruction. The study aims to describe sclerokeratoplasty outcomes in severely diseased eyes.
Denise Loya-Garcia +7 more
doaj +1 more source
Advanced Electronic Materials, EarlyView.The integration of ultra‐flexible, all‐organic, field‐effect transistor‐based strain sensors to soft structures is reported for the development of sensorized soft robots. The envisaged application is the development of next‐generation, controllable, and observable soft robotic catheters for endoscopic applications, such as drug delivery. Mechanical and
Usama Mahmood +5 more
wiley +1 more source
From Flexible to Conformable Pressure Sensors: Mechanisms, Materials, and Biomedical Applications
Advanced Electronic Materials, EarlyView.This review highlights recent progress, challenges and future opportunities in pressure sensing for advanced biomedical applications. We summarize key transduction mechanisms and emerging material strategies, discuss representative wearable and implantable applications for continuous physiological monitoring and provide a focused perspective on barrier
Rishabh B. Mishra +2 more
wiley +1 more source
Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.Quantitative phase maps of single cells recorded in flow cytometry modality feed a hierarchical architecture of machine learning models for the label‐free identification of subtypes of ovarian cancer. The employment of a priori clinical information improves the classification performance, thus emulating the clinical application of liquid biopsy during ...
Daniele Pirone +11 more
wiley +1 more source