Results 61 to 70 of about 2,347 (263)

Thermochemistry of MgCr2O4, MgAl2O4, MgFe2O4 spinels in SO2-O2-SO3 atmosphere [PDF]

open access: yesProcessing and Application of Ceramics, 2016
The present paper investigates high-temperature sulphate corrosion of basic refractory ceramics containing magnesium spinels (MgAl2O4, MgFe2O4, MgCr2O4 and their solid solutions) widely used in metallurgy, chemical, ceramic and glass industry. This group
Anna Gerle   +2 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Refractory Celiac Disease

open access: yesCurrent Opinion in Oncology, 2013
Concept of refractory coeliac disease (RCD) emerged in the past decade and refers to persistence of malnutrition and intestinal villous atrophy for more than 1 year strict gluten-free diet in coeliac patients. Diagnosis of this condition remains difficult and conditions treatment and follow-up.RCD has been subdivided into two subgroups according to the
Georgia, Malamut, Christophe, Cellier
openaire   +5 more sources

Refractoriness and Neural Precision [PDF]

open access: yesThe Journal of Neuroscience, 1998
The response of a spiking neuron to a stimulus is often characterized by its time-varying firing rate, estimated from a histogram of spike times. If the cell’s firing probability in each small time interval depends only on this firing rate, one predicts a highly variable response to repeated trials, whereas many neurons show much greater fidelity ...
Michael J. Berry II, Markus Meister
openaire   +3 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Uso do resíduo de catalisador de processo de craqueamento catalítico fluído de hidrocarbonetos em refratários silicoaluminosos Use of catalyst waste from hydrocarbon fluid catalytic cracking process in alumina-silica refractories

open access: yesCerâmica, 2009
Este trabalho objetivou o desenvolvimento de metodologia para o aproveitamento do resíduo de catalisador de craqueamento de hidrocarbonetos, na produção de refratários silicoaluminosos.
L. P. Garcia   +2 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha   +4 more
wiley   +1 more source

The effect of microsilica and refractory cement content on the properties of andalusite based Low Cement Castables used in aluminum casthouse O efeito do teor de microsílica e de cimento refratário nas propriedades de LCCs usados em moldagem de alumínio

open access: yesCerâmica, 2010
The bonding system in low cement castables is achieved by the use of calcium aluminate cement, microsilica and reactive alumina. The lime/silica ratio critically impacts the liquid phase formation at high temperatures and subsequently the corrosion ...
E. A. Firoozjaei   +3 more
doaj   +1 more source

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