Results 61 to 70 of about 19,857 (307)

Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan, Lydie Da Costa, Ludivine David Nguyen, Heloise Chosseler, Audrey Riquet, Benedicte Bruno, Melissa Barbati   +6 more
wiley   +1 more source

The Feasibility of Reclaiming Shell Material from Investment Casting [PDF]

, 1992
This report examines the feasibility of investment shell component reclamation. Shell material components and their compositions are investigated with an industry survey, a study of the available literature, and analysis of specimen shell materials ...
Peters, Timothy M., Twarog, Daniel L.
core  

The Role of Invasive Procedures in the Treatment of Complicated Gastrointestinal Graft‐Versus‐Host Disease in Pediatric Patients

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Gastrointestinal graft‐versus‐host disease (GI GVHD) following hematopoietic stem cell transplant is typically managed with medical therapy, but surgery and angioembolization may be warranted in selected cases with life‐threatening complications.
Gaia Brunetti, Giorgio Persano, Chiara Grimaldi, Pier Luigi Di Paolo, Carmen Malaspina, Francesco Quagliarella, Valerio Balassone, Anna Chiara Iolanda Contini, Gian Luigi Natali, Rita Alaggio, Ivan Pietro Aloi, Tamara Caldaro, Alessandro Crocoli   +12 more
wiley   +1 more source

Uso do resíduo de catalisador de processo de craqueamento catalítico fluído de hidrocarbonetos em refratários silicoaluminosos Use of catalyst waste from hydrocarbon fluid catalytic cracking process in alumina-silica refractories

Cerâmica, 2009
Este trabalho objetivou o desenvolvimento de metodologia para o aproveitamento do resíduo de catalisador de craqueamento de hidrocarbonetos, na produção de refratários silicoaluminosos.
L. P. Garcia, R. T. da Cruz, S. R. Bragança   +2 more
doaj   +1 more source

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider, Amelie Alfert, Marc Hotfilder, Birgit Burkardt, Marcel te Vrugt   +4 more
wiley   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Predicting the frequencies of diverse exo-planetary systems

, 2007
Extrasolar planetary systems range from hot Jupiters out to icy comet belts more distant than Pluto. We explain this diversity in a model where the mass of solids in the primordial circumstellar disk dictates the outcome. The star retains measures of the
Beichman, C. A., Bryden, G., Fischer, D. A., Greaves, J. S., Wyatt, M. C.   +4 more
core   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

The effect of microsilica and refractory cement content on the properties of andalusite based Low Cement Castables used in aluminum casthouse O efeito do teor de microsílica e de cimento refratário nas propriedades de LCCs usados em moldagem de alumínio

Cerâmica, 2010
The bonding system in low cement castables is achieved by the use of calcium aluminate cement, microsilica and reactive alumina. The lime/silica ratio critically impacts the liquid phase formation at high temperatures and subsequently the corrosion ...
E. A. Firoozjaei, A. Saidi, A. Monshi, P. Koshy   +3 more
doaj   +1 more source

Effect of microsilica content on microstructure and properties of foamed ceramics with needle-like mullite [PDF]

Processing and Application of Ceramics, 2019
In this study, five foamed ceramics with struts containing needle-like mullite were prepared by direct-foaming method using white clay, industrial alumina and microsilica powder as raw materials.
Wenying Zhou, Wen Yan, Nan Li, Yuanbing Li, Yajie Dai, Zheng Zhang   +5 more
doaj   +1 more source