Results 71 to 80 of about 19,857 (307)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Nano-laminated BN modified graphite reinforced unfired MgO–C refractories: Preparation, properties and strengthening mechanism

Journal of Materials Research and Technology
To solve the problem of deterioration of oxidation resistance and thermal shock resistance caused by low carbonization of MgO–C refractories, nano-laminated BN modified graphite was prepared by the molten salt method to reinforce unfired MgO–C ...
Shutong Fan, Chengji Deng, Chao Yu, Zhenglong Liu, Jun Ding   +4 more
doaj   +1 more source

Refractory concrete: A material that offers new ceramic opportunities. [PDF]

, 2011
Refractory concretes (RC) are industrial materials used most commonly in high temperature applications, primarily in the steel and glass industries. In most cases they are a mix of refractory aggregate’s chosen for specific hot engineering applications ...
Alkandari, Fahad, Bremner, Alasdair
core  

Chemical signatures of planets: beyond solar-twins [PDF]

, 2013
Elemental abundance studies of solar twin stars suggest that the solar chemical composition contains signatures of the formation of terrestrial planets in the solar system, namely small but significant depletions of the refractory elements.
Asplund, M., Melendez, J., Ramirez, I.
core   +3 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

New solar metallicity measurements

, 2019
In the past years, a systematic downward revision of the metallicity of the Sun has led to the "solar modeling problem", namely the disagreement between predictions of standard solar models and inferences from helioseismology.
Vagnozzi, Sunny
core   +1 more source

Evolved stars and the origin of abundance trends in planet hosts [PDF]

, 2016
Tentative evidence that the properties of evolved stars with planets may be different from what we know for MS hosts has been recently reported. We aim to test whether evolved stars with planets show any chemical peculiarity that could be related to the ...
Maldonado, J., Villaver, E.
core   +4 more sources

This Is Not a Myeloproliferative Neoplasm…

Pediatric Blood &Cancer, EarlyView.
Stephanie Juané Kennedy
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Fluencia en materiales refractarios

Boletín de la Sociedad Española de Cerámica y Vidrio, 2013
Refractory materials are widely used in various industrial fields due to their outstanding properties and performance in aggressive environments. However, although creep resistance is one of the most important properties for the selection of these ...
Tomba Martínez, A. G., Luz, A. P., Pandolfelli, V. C.   +2 more
doaj   +1 more source