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Concept of refractory coeliac disease (RCD) emerged in the past decade and refers to persistence of malnutrition and intestinal villous atrophy for more than 1 year strict gluten-free diet in coeliac patients. Diagnosis of this condition remains difficult and conditions treatment and follow-up.RCD has been subdivided into two subgroups according to the
Georgia, Malamut, Christophe, Cellier
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BackgroundCrohn’s disease (CD) is a chronic nonspecific inflammatory bowel disease (IBD) with an increasing incidence worldwide. The etiology of CD is still obscure, but microbial dysbiosis has been recognized as an essential factor contributing to CD ...
Kai Xia +8 more
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Fecal microbiota transplant promotes response in immunotherapy-refractory melanoma patients
New fecal microbiota for cancer patients The composition of the gut microbiome influences the response of cancer patients to immunotherapies. Baruch et al. and Davar et al.
E. Baruch +31 more
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In adoptive T cell therapy (ACT), the transfer of tumor-specific T cells is paralleled by the conditioning regimen to increase therapeutic efficacy. Pre-conditioning depletes immune-suppressive cells and post-conditioning increases homeostatic signals to
Seon-Hee Kim +4 more
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Background: Lobectomy with preservation of the contralateral lobe has already become the most preferred surgical method for patients with low-risk thyroid cancer. The incidence of and risk factors for the development of hypothyroidism after lobectomy for
Soo Young Kim +6 more
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Evolution of reduction process from tungsten oxide to ultrafine tungsten powder via hydrogen
Herein, the evolution of reduction process of ultrafine tungsten powder in industrial conditions was investigated. The transition process of morphology and composition was examined via SEM, XRD, and calcination experiments.
Wang Yue +3 more
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Crohn’s Disease Complicated by Rare Types of Intestinal Obstruction: Two Case Reports
Intestinal obstruction is one of the most common complications of Crohn’s disease (CD), jeopardizing the quality of life of patients. Numerous factors may contribute to intestinal obstruction in CD.
Kai Xia +9 more
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Chronic migraine: treatability, refractoriness, pseudo-refractoriness [PDF]
Chronic migraine (CM), a highly disabling condition affecting 2-3% of the general population, represents a difficult-to-treat disorder for its unclear pathophysiology, complex comorbidities, and disappointing response to available pharmacological treatments[1]. High quality evidence (≥2 RCTs) recommends the prophylactic use of onabotulinum toxin A (155-
Barbanti, Piero +4 more
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Along with the extensive application of energy storage devices, the spent lithium-ion batteries (LIBs) are unquestionably classified into the secondary resources due to its high content of several valuable metals.
Long Ye +6 more
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CRISPR-engineered T cells in patients with refractory cancer
CRISPR takes first steps in humans CRISPR-Cas9 is a revolutionary gene-editing technology that offers the potential to treat diseases such as cancer, but the effects of CRISPR in patients are currently unknown. Stadtmauer et al. report a phase 1 clinical
E. Stadtmauer +40 more
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