Results 31 to 40 of about 836,249 (298)

Long-term safety and activity of axicabtagene ciloleucel in refractory large B-cell lymphoma (ZUMA-1): a single-arm, multicentre, phase 1-2 trial.

The Lancet Oncology, 2019
BACKGROUND Axicabtagene ciloleucel is an autologous anti-CD19 chimeric antigen receptor (CAR) T-cell therapy. In the previous analysis of the ZUMA-1 registrational study, with a median follow-up of 15·4 months (IQR 13·7-17·3), 89 (82%) of 108 assessable ...
F. Locke, A. Ghobadi, C. Jacobson, D. Miklos, L. Lekakis, O. Oluwole, Yi Lin, I. Braunschweig, B. Hill, J. Timmerman, A. Deol, P. Reagan, P. Stiff, I. Flinn, U. Farooq, A. Goy, P. Mcsweeney, J. Muñoz, T. Siddiqi, J. Chavez, A. Herrera, N. Bartlett, J. Wiezorek, L. Navale, A. Xue, Yi-zhou Jiang, A. Bot, J. Rossi, Jenny J. Kim, W. Go, S. Neelapu   +30 more
semanticscholar   +1 more source

Cholesterol Synthesis Is Important for Breast Cancer Cell Tumor Sphere Formation and Invasion

Biomedicines, 2022
Breast cancer has a high risk of recurrence and distant metastasis after remission. Controlling distant metastasis is important for reducing breast cancer mortality, but accomplishing this goal remains elusive.
Hee Yeon Kim, Sung Jin Bae, Ji-Woong Choi, Suji Han, Seung-Hyun Bae, Jae-Ho Cheong, Hyonchol Jang   +6 more
doaj   +1 more source

Role of heat treatment of hydroxyapatite powder prior to suspension preparation on the suspension flow behavior

Open Ceramics, 2022
One of the key issues involved in successfully achieving hydroxyapatite (HA) ceramic body without defects using colloidal processing technique, is the preparation of homogeneously high solid loading HA ceramic suspension.
Amira M.M. Amin, Dina H.A. Besisa, Ahmed A.M. El-Amir, Zaki I. Zaki, Yasser M.Z. Ahmed   +4 more
doaj   +1 more source

The effect of liquid glass on the deformation of refractory binder/Skystojo stiklo įtaka kaitrai atsparaus rišiklio deformacijoms

Journal of Civil Engineering and Management, 2001
The structure formation of a refractory binder of liquid glass, ferrochrome slag and dispersed chamotte has been studied. It has been found that there is a close relationship between the density of liquid glass used and sharp expansion of binder at the ...
Valentin Antonovič, Stasys Goberis
doaj   +1 more source

Pediatric refractory and super-refractory status epilepticus [PDF]

Seizure, 2019
To summarize the available evidence related to pediatric refractory status epilepticus (RSE) and super-refractory status epilepticus (SRSE), with emphasis on epidemiology, etiologies, therapeutic approaches, and clinical outcomes.Narrative review of the medical literature using MEDLINE database.RSE is defined as status epilepticus (SE) that fails to ...
Alejandra Vasquez, Raquel Farias-Moeller, William Tatum   +2 more
openaire   +2 more sources

Anti‐BCMA CAR T‐Cell Therapy bb2121 in Relapsed or Refractory Multiple Myeloma

New England Journal of Medicine, 2019
BACKGROUND Preclinical studies suggest that bb2121, a chimeric antigen receptor (CAR) T‐cell therapy that targets B‐cell maturation antigen (BCMA), has potential for the treatment of multiple myeloma. METHODS In this phase 1 study involving patients with
N. Raje, J. Berdeja, Yi Lin, D. Siegel, S. Jagannath, D. Madduri, M. Liedtke, J. Rosenblatt, M. Maus, Ashley Turka, L. Lam, R. Morgan, Kevin G. Friedman, M. Massaro, Julie Wang, G. Russotti, Zhihong Yang, T. Campbell, K. Hege, F. Petrocca, Travis Quigley, N. Munshi, J. Kochenderfer   +22 more
semanticscholar   +1 more source

Atomistic simulations of dislocation mobility in refractory high-entropy alloys and the effect of chemical short-range order

Nature Communications, 2021
Refractory high-entropy alloys (RHEAs) are designed for high elevated-temperature strength, with both edge and screw dislocations playing an important role for plastic deformation.
Sheng Yin, Yunxing Zuo, A. Abu-Odeh, Huijin Zheng, Xiang-Guo Li, Jun Ding, S. Ong, M. Asta, R. Ritchie   +8 more
semanticscholar   +1 more source

Thermo-Insulating Moulding Sand for thin Walled Castings

Archives of Metallurgy and Materials, 2014
In paper the selection of the composition and determination of main properties of novel moulding sand was described. The mail goal was to create moulding sand characterized by high thermal insulating properties in relations with low specific weight. This
Cholewa M., Szuter T.
doaj   +1 more source

Neutralization of SARS-CoV-2 with IgG from COVID-19-convalescent plasma

Scientific Reports, 2021
While there are various attempts to administer COVID-19-convalescent plasmas to SARS-CoV-2-infected patients, neither appropriate approach nor clinical utility has been established.
Kenji Maeda, Nobuyo Higashi-Kuwata, Noriko Kinoshita, Satoshi Kutsuna, Kiyoto Tsuchiya, Shin-ichiro Hattori, Kouki Matsuda, Yuki Takamatsu, Hiroyuki Gatanaga, Shinichi Oka, Haruhito Sugiyama, Norio Ohmagari, Hiroaki Mitsuya   +12 more
doaj   +1 more source

Understanding the effect of annealing temperature on Hot-Rolled pure Mo Sheet: Investigations from Texture, deformation Behavior, and mechanical properties

Materials & Design
This study investigates the effects of annealing temperature on the microstructural evolution, texture development, deformation behavior, and mechanical properties of hot-rolled pure Molybdenum (Mo) sheets.
Wenbin Liu, Yanchao Li, Wen Zhang, Xuanqiao Gao, Baojian Wang, Xin Zhang, Yichao Yang, Xiaohui Lin, Jianfeng Li, Hailong Xu   +9 more
doaj   +1 more source