Results 71 to 80 of about 906,079 (292)
High temperature compositions Patent [PDF]
, 1967 Method for producing refractory molybdenum ...
Long, R. A.
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Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Attachment system for silica tiles [PDF]
, 1982 An improved method for markedly increasing the bond strength between a rigid, porous refractory material and non-rigid substrate by densifying the face of the rigid material opposing the substrate is discussed.
Dotts, R. L., Holt, J. W.
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The Effect of a Refractory Period on the Power Spectrum of Neuronal Discharge [PDF]
, 1995 The interspike intervals in steady-state neuron firing are assumed to be independently and identically distributed random variables. In the simplest model discussed, each interval is assumed to be the sum of a random neuron refractory period and a ...
Bair, Wyeth, Franklin, Joel
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TREX1, a predator for treating MSI‐H tumors?
Molecular Oncology, EarlyView.Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya +2 more
wiley +1 more source
Tenascin C+ papillary fibroblasts facilitate neuro-immune interaction in a mouse model of psoriasis
Nature Communications, 2023 Dermal fibroblasts and cutaneous nerves are important players in skin diseases, while their reciprocal roles during skin inflammation have not been characterized.
Xiaojie Cai +16 more
doaj +1 more source
High temperature refractory member with radiation emissive overcoat [PDF]
, 1990 A radiation type heat dissipator for use in a plasma engine is formed of a refractory metal layer upon which there is deposited a radiation emissive coating made of a high emissivity material such as zirconium diboride. The radiation emissive coating has
Deininger, William D., King, David Q.
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A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Molecular Oncology, EarlyView.Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source
Test for a Low-grade Scheelite Ore with Improving the Grade of Concentrate by Optimization of Agents
Kuangchan zonghe liyongThere are 0.27% WO3 in a scheelite Ore. The grade of scheelite concentrate produced on site is 53.11%. Because the grade of the concentrate is low, the pricing coefficient of the concentrate is low. In order to improve the grade of scheelite concentrate,
Qihong XU +5 more
doaj +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source