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Neuromodulation for Refractory Epilepsy
Epilepsy Currents, 2021 Three neuromodulation therapies, all using implanted device and electrodes, have been approved to treat adults with drug-resistant focal epilepsy, namely, the vagus nerve stimulation in 1995, deep brain stimulation of the anterior nucleus of the thalamus (ANT-DBS) in 2018 (2010 in Europe), and responsive neurostimulation (RNS) in 2014.
Philippe Ryvlin, Lara E. Jehi
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Refractory Epilepsy: Clinical Overview [PDF]
Epilepsia, 2007 Summary: The incidence of refractory epilepsy remains high despite the influx of many new antiepileptic drugs (AEDs) over the past 10 years. Epidemiological data indicate that 20–40% of the patients with newly diagnosed epilepsy will become refractory to treatment.
Jacqueline French
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Is Refractory Epilepsy Preventable? [PDF]
Epilepsia, 2002 Summary: About a third of the patients diagnosed with epilepsy will not be fully controlled with antiepileptic drugs (AEDs), and many of them will have frequent and disabling seizures. These patients will undergo multiple drug trials, most often without complete seizure remission.
Santiago, Arroyo +7 more
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Coping with refractory epilepsy
Seizure, 1999 We investigated the coping behaviour and its correlation with demographic and illness-related data, depression, locus of control and psychosocial adaptation in 40 patients with intractable epilepsy with primarily or secondarily generalized tonic-clonic seizures.
Krakow, K. +2 more
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Continuing Burden of Refractory Epilepsy [PDF]
Annals of Pharmacotherapy, 2020 Epilepsy is one of the most common neurological diseases, and uncontrolled seizures remain a significant problem for one-third of patients with epilepsy on drug therapy. Ongoing seizures affect the morbidity and mortality of patients with epilepsy. Premature death is up to 3 times higher in those with epilepsy than in the general population. Quality of
Marnie T. Janson +1 more
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Approaches to refractory epilepsy
Annals of Indian Academy of Neurology, 2014 Epilepsy is one of the most common serious neurological conditions, and 30 to 40% of people with epilepsy have seizures that are not controlled by medication. Patients are considered to have refractory epilepsy if disabling seizures continue despite appropriate trials of two antiseizure drugs, either alone or in combination.
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Cannabidiol Treatment for Refractory Epilepsies in Pediatrics [PDF]
Frontiers in Pharmacology, 2020 Cannabis extracts in oil are becoming increasingly available, and, during the last years, there has been growing public and scientific interest about therapeutic properties of these compounds for the treatment of several neurologic diseases, not just epilepsy.
Raucci U. +9 more
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Treating refractory epilepsy in adults [PDF]
BMJ, 2006 The choice of drug or drug combinations is bewildering M ost adult patients with refractory epilepsy have partial (focal) seizures with or without secondary generalisation. During the 1970s and early 1980s studies showed that in 70-80% of adults with newly diagnosed epilepsy, seizures were controlled successfully by carefully monitored monotherapy ...
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The Management of Refractory Idiopathic Epilepsies [PDF]
Epilepsia, 2001 Summary: Idiopathic epilepsies comprise a wide variety of partial and generalized syndromes that have in common a known or presumed genetic etiology and the lack of overt abnormalities other than the epilepsy itself. Most of these epilepsies have a benign natural history and/or show a favorable response to antiepileptic drug (AED) therapy, but ...
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Neuroimaging evaluation in refractory epilepsy
The Neuroradiology Journal, 2015 Purpose To describe the application of neuroimaging analysis, compared to neuropsychological tests and video-electroencephalogram, for the evaluation of refractory epilepsy in a reference centre in Cali, Colombia. Methods Between March
Ana M, Granados +2 more
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