Bortezomib‐based chemotherapy achieved an 88.9% remission rate in Chinese pediatric patients with relapsed/refractory B‐cell acute lymphoblastic leukemia, enabling 62.5% of responders to bridge to transplantation, while T‐cell acute lymphoblastic leukemia showed no response.
Xingyu Zhao +5 more
wiley +1 more source
Quality of life in adults with refractory epilepsy in Thailand: a multicenter upcountry nationwide study. [PDF]
Phabphal K +8 more
europepmc +1 more source
Apigenin Protects Hypertensive Intracerebral Hemorrhage by Regulating Trx1 Through Binding to PRDX2
ABSTRACT Intracerebral hemorrhage (ICH) remains the most severe stroke subtype with high mortality and disability rates. Although apigenin has shown cerebroprotective potential in preclinical studies, its mechanism of action, particularly in hypertensive ICH, remains poorly understood.
Hao‐chen Xu +6 more
wiley +1 more source
Laser interstitial thermal therapy (LITT) for refractory epilepsy due to focal cortical dysplasia in an infant. [PDF]
Chilappa R +5 more
europepmc +1 more source
Potential value of slow‐wave sleep in management of chronic insomnia disorder
Abstract Chronic insomnia disorder (CID), acknowledged as the most common sleep disorder, has traditionally been diagnosed and managed with a focus on reducing sleep onset latency and extending total sleep duration. However, the critical importance of slow‐wave sleep (SWS), a key indicator of objective sleep quality, has been largely overlooked in ...
Liping Zhang +4 more
wiley +1 more source
Case report: Surgical disconnection for medically refractory epilepsy in ARID1B-related Coffin-Siris syndrome. [PDF]
Ye XL +6 more
europepmc +1 more source
Shared struggles: Parallels in caregiver burden between canine and paediatric epilepsy
Abstract Background Disease‐specific aspects of pet owners’ caregiver burden could be missed by generic burden measures. This study aimed to assess whether a framework developed to describe caregiver burden in parents of children with epilepsy was applicable to caregivers of dogs with epilepsy.
Zoe Belshaw, Rowena M. A. Packer
wiley +1 more source
A Descriptive Study of Caregivers' Awareness, Practices, Challenges Faced, and Methods of Adherence to the Ketogenic Diet in Children with Refractory Epilepsy. [PDF]
Alafif N +10 more
europepmc +1 more source
Abstract Gabapentin (GBP) is widely prescribed off‐label, and cases of misuse, abuse, self‐medication, and intentional self‐harm have been reported. This study aimed to develop and validate a simple GC‐MS method for the determination of GBP in plasma and vitreous humor (VH) and to explore the relationship between concentrations in both matrices in ...
Pamela Cabarcos‐Fernández +4 more
wiley +1 more source
Decanoic acid-enriched ketogenic diet in refractory epilepsy. [PDF]
Shin HJ +8 more
europepmc +1 more source

