Results 51 to 60 of about 356,945 (257)

GRIA2 Variant Associated With Paradoxical Response to Perampanel Expanding the Spectrum of GRIA2‐Related Epileptic Encephalopathy: Case Report and Literature Review

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Introduction GRIA2 encodes the GluA2 ionotropic α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid (AMPA) receptor subunit. Pathogenic GRIA2 variants cause epilepsy, developmental delay, and neurobehavioral disorders. Characterizations of clinical features, including seizure types and their treatments, in patients with GRIA2‐related ...
Sai Srihitha Dommata, Chhitij Tiwari, Zheng Fan, Muge Gucsavas‐Calikoglu, Yael Shiloh‐Malawsky, Kimberly S. Foss, Stephanie N. Peck, Erin L. Heinzen, Chon Lee, Senyene E. Hunter   +9 more
wiley   +1 more source

Cost analysis of epilepsy surgery and of vigabatrin treatment in patients with refractory partial epilepsy

, 1996
The paper discusses the health-economic analysis of two treatments for refractory epilepsy from methodological and ethical ...
Ben-Menachem, Elinor,, Malmgren, Helge,, Granqvist, Roland, Hedström, Anders,, Malmgren, Kristina,   +4 more
core  

Opsoclonus in Pediatric Patients: Differential Diagnosis and a Practical Approach to Evaluation

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Opsoclonus is an ocular dyskinesia characterized by involuntary, arrhythmic, multidirectional saccades. In pediatrics, opsoclonus is most commonly attributed to the rare neuroinflammatory disorder opsoclonus‐myoclonus‐ataxia syndrome (OMAS), typically considered a paraneoplastic syndrome associated with neural crest tumors. However, opsoclonus
Aubrey C. Reed, Supreet S. Randhawa, Jason H. Peragallo, Prabhumallikarjun Patil, Grace Gombolay, Varun Kannan   +5 more
wiley   +1 more source

Rufinamide for the treatment of refractory epilepsy secondary to neuronal migration disorders

, 2014
To evaluate the efficacy and tolerability of add-on rufinamide in children with refractory epilepsy symptomatic of neuronal migration ...
Verrotti, Alberto, Curatolo, Paolo, Di Gennaro, Giancarlo, Di Gennaro, G, Federico Vigevano, Matricardi, Sara, Spalice, A, Cusmai, R, Pruna, D, Parisi, Pasquale, Raffaella Cusmai, Coppola, G, Parisi, P, Giancarlo Di Gennaro, Vigevano, Federico, Alberto Verrotti, Alfredo D'Aniello, Pruna, Dario, D'Aniello, Alfredo, COPPOLA, Giangennaro, Battaglia, D, Verrotti, A, Alberto Spalice, Coppola, G., Paolo Curatolo, Curatolo, P, Moavero, Romina, Sara Matricardi, Cusmai, Raffaella, Giangennaro Coppola, Battaglia, Domenica, Vigevano, F, Battaglia, Domenica Immacolata, Romina Moavero, Domenica Battaglia, Dario Pruna, Moavero, R, Spalice, Alberto, Matricardi, S, D'Aniello, A   +39 more
core   +1 more source

Stepwise administration of de novo ketogenic parenteral nutrition for refractory epilepsy during prolonged bowel rest following duodenal perforation. [PDF]

JPGN Rep
Abstract Ketogenic diet is an established therapy for pediatric patients with intractable epilepsy. By shifting energy metabolism from glucose to fat, the diet increases the production of ketone bodies, which alters neuronal excitability and modulates neurotransmitter signaling, thereby raising the seizure threshold.
Sheikh Z, Sewak S, Mein DN, Matsumoto JH, Chan AP.   +4 more
europepmc   +2 more sources

Long-term effects of vagus nerve stimulation in refractory pediatric epilepsy: A single-center experience

, 2020
Introduction: Vagus nerve stimulation (VNS) has been used as an adjunctive therapy for both children and adults with refractory epilepsy, over the last two decades.
Bilginer, Burçak, Konuşkan, Bahadır, Turanli, G, Ardicli, D., Konuskan, B., Karli Oguz, K, Saygi, S, Oguz, Kader Karli, Ardıçlı, Didem, Karlı Oğuz, Kader, SAYGI, SERAP, Akalan, Nejat, Saygı, Serap, Yalnizoglu, D, Turanlı, Güzide, Yalnızoğlu, Dilek, YALNIZOĞLU, DİLEK, Topçu, Meral, KONUŞKAN, BAHADIR, Akalan, N, Turanli, Guezide, ARDIÇLI, DİDEM, Oğuz, Kader Karlı   +22 more
core   +1 more source

Efficacy of fenfluramine in a pediatric epilepsy patient with a pathogenic SV2A variant: A case report

Epileptic Disorders, EarlyView.
Abstract Pathogenic SV2A gene variants have been reported as causes of epilepsy and are often associated with drug resistance and susceptibility to fever‐related seizures. No highly effective treatments have been established for this condition. We report a female patient with a family history of epilepsy who developed generalized seizures associated ...
Takayuki Mori, Hiroshi Terashima, Yu kakimoto, Mitsuhiro Kato, Shumpei Uchino   +4 more
wiley   +1 more source

Report of the 2003 National Conference on Public Health and Epilepsy [PDF]

I. Executive Summary -- II. Introduction -- III. Living Well with Epilepsy II Conference -- -- IV. Review and Recommendations -- -- Workgroup A: Early Recognition, Diagnosis and Treatment -- -- Workgroup B: Epidemiology and Surveillance -- -- Workgroup C:
National Conference on Public Health and Epilepsy (2003 : Baltimore, MD)
core  

Super-Refractory Status Epilepticus: An Atypical Presentation and Case-Based Review

, 2015
Super-refractory status epilepticus is known to typically arise either from a distinct underlying cause or, in patients with no history of epilepsy, from no overt cause.
Olusegun OYEWOLE, Fola A. FAPONLE, Chiazor Udochukwu ONYIA, Ayo M. ADEBIYI, Morenikeji A. KOMOLAFE   +4 more
core   +1 more source

Platelet activating factor and monocyte chemoattractant protein-1 in children with refractory epilepsy [PDF]

, 2014
Background: Epilepsy is an important common and diverse group of symptom complexes characterized by recurrent spontaneous seizures. It is estimated that about 5-10% of all cases of epilepsy eventually become refractory.
Alm El-Din, Rasha A, Abd El-Aziz, Sahar A   +1 more
core   +1 more source