Results 121 to 130 of about 19,908 (254)

Predicting outcome in adults with status epilepticus [PDF]

, 2018
Status epilepticus (SE) is a life-threatening state of persisting or repetitive seizure activity with often permanent altered level of consciousness. Despite its high morbidity and mortality there is no consensus about the best strategy to treat specific
Rüegg, S., Sutter, R.
core  

Rapamycin attenuates acute seizure-induced astrocyte injury in mice in vivo [PDF]

, 2017
Astrocytes have been implicated in epileptogenesis and seizure-induced brain injury. Pathological studies reveal a variety of structural abnormalities in astrocytes, such as vacuolization and astrogliosis.
Guo, Dongjun, Wong, Michael, Zou, Jia
core   +2 more sources

Unique deficits in place coding across subfields of the hippocampus in a mouse model of temporal lobe epilepsy

Epilepsia, EarlyView.
Abstract Objective Memory problems are comorbid with temporal lobe epilepsy (TLE). Animal models of TLE reveal impairments in spatial firing fields of hippocampal place cells, providing a potential neural substrate for memory problems. Each subfield of the hippocampus carries out unique aspects of spatial memory, yet little is known about how ...
Brittney L. Boublil, Margaret M. Donahue, Cathy B. Dang, Gergely Tarcsay, Laura A. Ewell   +4 more
wiley   +1 more source

Epilepsy syndromes classification

Epilepsia Open, EarlyView.
Abstract Epilepsy syndromes are distinct electroclinical entities which have been recently defined by the International League Against Epilepsy Nosology and Definitions Task Force. Each syndrome is associated with “a characteristic cluster of clinical and EEG features, often supported by specific etiologic findings”.
Elaine C. Wirrell, Nicola Specchio, Rima Nabbout, Phillip L. Pearl, Kate Riney   +4 more
wiley   +1 more source

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

Epilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza, Greta Volpedo, Antonella Riva, Pasquale Striano, Annamaria Vezzani   +4 more
wiley   +1 more source

The Established Status Epilepticus Trial 2013 [PDF]

, 2013
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/99653/1/epi12288 ...
Bleck, Thomas, Chamberlain, James, Cloyd, James, Cock, Hannah, Connor, Jason, Elm, Jordan, Fountain, Nathan, Jones, Elizabeth, Kapur, Jaideep, Lowenstein, Daniel, Shinnar, Shlomo, Silbergleit, Robert, Treiman, David, Trinka, Eugen   +13 more
core   +1 more source

Genetic epilepsies with myoclonic seizures: Mechanisms and syndromes

Epilepsia Open, EarlyView.
Abstract Genetic epilepsy with myoclonic seizures encompasses a heterogeneous spectrum of conditions, ranging from benign and self‐limiting forms to severe, progressive disorders. While their causes are diverse, a significant proportion stems from genetic abnormalities.
Antonietta Coppola, Marica Rubino, Antonella Riva, Pasquale Striano   +3 more
wiley   +1 more source

Status Epilepticus Type, Etiology, and Treatment: One-year Data

Archives of Epilepsy
Objective: This study aimed to review the demographic characteristics, type, and etiology of status epilepticus (SE) cases followed in our hospital for a period of 1 year and to reveal the factors affecting the prognosis of the patients.
Didar Çolakoğlu, Humay İsmayilzade, Berk Büke, Kadriye Ağan, İpek Midi   +4 more
doaj   +1 more source

Audit of use of stiripentol in adults with Dravet syndrome [PDF]

, 2016
OBJECTIVES: There are very few data available in the literature on the use of stiripentol in adults with Dravet syndrome (DS). DS cases are increasingly recognized in adulthood, and more children with DS now survive to adulthood. The aim of the study was
Balestrini, S, Sisodiya, SM
core   +1 more source

Status epilepticus: Updates on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley   +1 more source