Results 131 to 140 of about 59,639 (336)

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source

Early polytherapy for benzodiazepine-refractory status epilepticus. [PDF]

, 2019
The transition from single seizures to status epilepticus (SE) is associated with malaptive trafficking of synaptic gamma-aminobutyric acid (GABAA) and glutamate receptors. The receptor trafficking hypothesis proposes that these changes are key events in
Baldwin, Roger, de Araujo Furtado, Marcio, Franco-Estrada, Ireri, Lumley, Lucille, Naylor, David, Niquet, Jerome, Rossetti, Franco, Schultz, Mark, Suchomelova, Lucie, Wasterlain, Claude G   +9 more
core   +1 more source

Post–COVID‐19 inflammatory syndrome manifesting as refractory status epilepticus

Epilepsia, 2020
There have been multiple descriptions of seizures during the acute infectious period in patients with COVID‐19. However, there have been no reports of status epilepticus after recovery from COVID‐19 infection. Herein, we discuss a patient with refractory
Elizabeth Carroll, H. Neumann, M. Aguero-Rosenfeld, J. Lighter, B. Czeisler, Kara Melmed, A. Lewis   +6 more
semanticscholar   +1 more source

Network structure determines patterns of network reorganization during adult neurogenesis [PDF]

, 2009
New cells are generated throughout life and integrate into the hippocampus via the process of adult neurogenesis. Epileptogenic brain injury induces many structural changes in the hippocampus, including the death of interneurons and altered connectivity ...
Ben-Jacob, Eshel, Parent, Jack M., Sander, Leonard M., Schneider-Mizell, Casey M., Zochowski, Michal   +4 more
core  

Spatial variation in automated burst suppression detection in pharmacologically induced coma [PDF]

, 2017
Burst suppression is actively studied as a control signal to guide anesthetic dosing in patients undergoing medically induced coma. The ability to automatically identify periods of EEG suppression and compactly summarize the depth of coma using the burst
An, Jingzhi, Brown, Emery Neal, Jonnalagadda, Durga, Moura, Valdery, Purdon, Patrick L., Westover, M. Brandon   +5 more
core   +1 more source

Neurodevelopmental outcome of perinatal intracranial haemorrhage in patients born at term: A prospective study

Developmental Medicine &Child Neurology, EarlyView.
Abstract Aim To assess the neurological and neurodevelopmental outcome of infants born at term with perinatal intracranial haemorrhage (pICH) and examine the clinical and neuroimaging associations. Method A prospective, consecutive, single‐center observational study of longitudinally followed children with pICH identified in the fetal or neonatal ...
Stephanie Libzon, Shelly I. Shiran, Aviva Fattal‐Valevski, Nira Schneebaum‐Sender, Jonathan Roth, Shlomi Constantini, Gustavo Malinger, Karina Krajden Haratz, Liat Ben Sira, Moran Hausman‐Kedem   +9 more
wiley   +1 more source

Comparing the Effect of Intravenous Midazolam with Rectal Sodium Valproate in Controlling of Children with Refractory Status Epilepticus

Journal of Research in Medical Sciences, 2006
Background: Refractory status epilepticus usually defined as a seizure lasting at least 60 minutes which is uncontrollable by Diazepam, Phenytoin, or Phenobarbital.
T Mahmoudian, M Najafian
doaj  

A Randomized Trial for the Treatment of Refractory Status Epilepticus [PDF]

, 2018
Background: Refractory status epilepticus (RSE) has a mortality of 16-39%; coma induction is advocated for its management, but no comparative study has been performed. We aimed to assess the effectiveness (RSE control, adverse events) of the first course
Bertschi, Manuel, Lee, Jong, Michaelides, Costas, Milligan, Tracey, Rossetti, Andrea, Vulliémoz, Serge   +5 more
core  

An interview with Thomas Foutz, 2025 Epilepsia open prize winner for basic science research

Epilepsia Open, EarlyView.
Merab Kokaia, Piero Perucca
wiley   +1 more source

ATAD3 duplications bridge mitochondrial diseases and Aicardi–Goutières syndrome

Developmental Medicine &Child Neurology, EarlyView.
ATAD3 locus duplications cause a severe neonatal mitochondrial disorder with neuroimaging features resembling interferonopathies, and suggest a mitochondrial nucleic acid‐triggered interferon response. Abstract A recurrent 68‐kb heterozygous duplication of the ATAD3 locus has been implicated in a mitochondrial disorder characterized by prenatal or ...
Pauline Planté‐Bordeneuve, Claire‐Marine Bérat, Sylvain Hanein, Cyril Gitiaux, ATAD3 Study Group, Julie Steffann, Isabelle Desguerre, Agnès Rötig, Nathalie Boddaert, Giulia Barcia, Brian Sperelakis‐Beedham, Zahra Assouline, Marie‐Thérèse Abi‐Warde, Rukhshona Abdullazoda, Agnès Guichet, Céline Bris, Aurélien Caux, Marlène Rio, Jérémy Bertrand, Pauline Gaignard, Alice Lepelley, Arnold Munnich, Manuel Schiff, Isabelle Desguerre, Agnès Rötig, Nathalie Boddaert, Giulia Barcia   +26 more
wiley   +1 more source