Results 141 to 150 of about 59,639 (336)
Abstract Objective Large language models (LLMs) have recently gained attention for clinical decision‐making and diagnosis. This study evaluates the performance of the recently updated LLM Chat Generative Pre‐Trained Transformer‐4omni (ChatGPT‐4o) in predicting clinical outcomes in patients with status epilepticus and compares its prognostic performance
Simon A. Amacher+10 more
wiley +1 more source
A 20-year-old woman with Dravet syndrome and multiple prior episodes of status epilepticus presented to our hospital in November 2018 in super-refractory status epilepticus.
David Millett, Suzanne Pach
doaj
Robust photoregulation of GABA(A) receptors by allosteric modulation with a propofol analogue. [PDF]
Photochemical switches represent a powerful method for improving pharmacological therapies and controlling cellular physiology. Here we report the photoregulation of GABA(A) receptors (GABA(A)Rs) by a derivative of propofol (2,6-diisopropylphenol), a ...
Bruzik, Karol S+8 more
core +2 more sources
Community‐onset pediatric status epilepticus: Barriers to care and outcomes in a real‐world setting
Abstract Objective Status epilepticus (SE) is a neurological emergency in childhood, often leading to neuronal damage and long‐term outcomes. The study aims to identify barriers in the pre‐hospital and in‐hospital management of community‐onset pediatric SE and to evaluate the effectiveness of pediatric scores on outcomes prediction.
Anna Fetta+12 more
wiley +1 more source
Effect of reduction of antiepileptic drugs in patients with drug-refractory epilepsy [PDF]
PurposeThe present study was conducted with the aim of evaluating the effects of reducing the number of antiepileptic drugs (AEDs) administered to patients with drug-refractory epilepsy (DRE) during their admission and document any change in seizure ...
Dash, Deepa+4 more
core +1 more source
Cortical hemodynamics of electrographic status epilepticus in the critically ill
Abstract Objectives The pathophysiological mechanisms of status epilepticus (SE) underlying potential brain injury remain largely unclear. This study aims to employ functional near‐infrared spectroscopy (fNIRS) combined with video‐electroencephalography (vEEG) to monitor brain hemodynamics continuously and non‐invasively in critically ill adult ...
Ali Kassab+6 more
wiley +1 more source
Super-Refractory Status Epilepticus: An Atypical Presentation and Case-Based Review
Super-refractory status epilepticus is known to typically arise either from a distinct underlying cause or, in patients with no history of epilepsy, from no overt cause.
Chiazor Udochukwu ONYIA+4 more
doaj +1 more source
Statins are associated with decreased mortality risk after status epilepticus. [PDF]
BACKGROUND AND PURPOSE: Statins display anti-inflammatory and anti-epileptogenic properties in animal models, and may reduce the epilepsy risk in elderly humans; however, a possible modulating role on outcome in patients with status epilepticus (SE) has ...
Alvarez, V.+4 more
core +1 more source
Abstract Objective The STEPPER (Status Epilepticus in Emilia‐Romagna) study aimed to investigate the clinical characteristics, prognostic factors, and treatment approaches of status epilepticus (SE) in adults of the Emilia‐Romagna region (ERR), Northern Italy.
Lidia Di Vito+56 more
wiley +1 more source
Innate and adaptive immunity in human epilepsies [PDF]
Inflammatory mechanisms have been increasingly implicated in the origin of seizures and epilepsy. These mechanisms are involved in the genesis of encephalitides in which seizures are a common complaint.
Bauer, J.+7 more
core +2 more sources