Results 21 to 30 of about 59,639 (336)

Treatment of new onset refractory status epilepticus/febrile infection‐related epilepsy syndrome with tocilizumab in a child and a young adult

Epilepsia, 2023
New onset refractory status epilepticus (NORSE) is a rare and devastating condition occurring in a previously healthy patient. It is called febrile infection‐related epilepsy syndrome (FIRES) when preceded by a febrile infection.
Marie-Laure Girardin, T. Flamand, Ombeline Roignot, Marie-Thérèse Abi Wardé, V. Mutschler, P. Voulleminot, M. Guillot, V. Dinkelacker, A. de Saint-Martin   +8 more
semanticscholar   +1 more source

Association Between Induced Burst Suppression and Clinical Outcomes in Patients With Refractory Status Epilepticus

Neurology, 2023
Background and Objectives To investigate the frequency of induced EEG burst suppression pattern during continuous IV anesthesia (IVAD) and associated outcomes in adult patients treated for refractory status epilepticus (RSE).
U. Fisch, Anja L. Jünger, Sira M. Baumann, S. Semmlack, G. M. De Marchis, S. Hunziker, S. Rüegg, S. Marsch, R. Sutter   +8 more
semanticscholar   +1 more source

International consensus recommendations for management of new onset refractory status epilepticus including febrile infection‐related epilepsy syndrome: Statements and supporting evidence

Epilepsia, 2022
This study was undertaken to develop consensus‐based recommendations for the management of adult and pediatric patients with new onset refractory status epilepticus (NORSE)/febrile infection‐related epilepsy syndrome (FIRES) based on best evidence and ...
R. Wickstrom, O. Taraschenko, R. Dilena, E. Payne, N. Specchio, R. Nabbout, S. Koh, N. Gaspard, L. Hirsch, S. Auvin, A. van Baalen, E. Beghi, S. Benseler, P. Bergin, Tom Bleck, A. Brunklaus, R. H. Caraballo, M. Cervenka, Daniel Costello, F. Drislane, R. Farias-Moeller, William Gallantine, E. Gilmore, T. Gofton, M. A. P. Jiménez, S. Hocker, M. Kaliakatsos, M. Kellogg, Jong Woo Lee, T. Loddenkemper, S. Meletti, Masashi Mizugushi, E. Muscal, J. Riviello, E. Rosenthal, Andrea O. Rossetti, Stefan Ruegg, Rana R. Said, C. Sculier, Sarah E. Schmitt, S. Schuele, Coral M. Stredny, E. Trinka, Mark Wainwright, Stephen A. VanHaerents, Elisabeth Wells, E. Wirrell, S. Zuberi   +47 more
semanticscholar   +1 more source

International consensus recommendations for management of new onset refractory status epilepticus (NORSE) including febrile infection‐related epilepsy syndrome (FIRES): Summary and clinical tools

Epilepsia, 2022
To develop consensus‐based recommendations for the management of adult and pediatric patients with new‐onset refractory status epilepticus (NORSE)/febrile infection‐related epilepsy syndrome (FIRES) based on best available evidence and expert opinion.
R. Wickström, O. Taraschenko, R. Dilena, E. Payne, N. Specchio, R. Nabbout, S. Koh, N. Gaspard, L. Hirsch, S. Auvin, A. van Baalen, E. Beghi, S. Benseler, P. Bergin, T. Bleck, A. Brunklaus, R. H. Caraballo, M. Cervenka, Daniel Costello, F. Drislane, R. Farias-Moeller, William Gallantine, E. Gilmore, T. Gofton, M. A. P. Jiménez, S. Hocker, M. Kaliakatsos, M. Kellogg, Jong Woo Lee, T. Loddenkemper, S. Meletti, Masashi Mizugushi, E. Muscal, J. Riviello, E. Rosenthal, Andrea O. Rossetti, Stefan Ruegg, Rana R. Said, C. Sculier, Sarah E. Schmitt, S. Schuele, Coral M. Stredny, E. Trinka, Mark Wainwright, Stephen A. VanHaerents, Elisabeth Wells, E. Wirrell, S. Zuberi   +47 more
semanticscholar   +1 more source

Review and standard operating procedures for collection of biospecimens and analysis of biomarkers in new onset refractory status epilepticus

Epilepsia, 2023
New onset refractory status epilepticus (NORSE), including its subtype with a preceding febrile illness known as febrile infection‐related epilepsy syndrome (FIRES), is one of the most severe forms of status epilepticus.
A. Hanin, Jorge Céspedes, Yashwanth Pulluru, Margaret T Gopaul, E. Aronica, D. DeCampo, I. Helbig, C. Howe, A. Huttner, S. Koh, V. Navarro, O. Taraschenko, A. Vezzani, M. Wilson, J. Xian, N. Gaspard, L. Hirsch   +16 more
semanticscholar   +1 more source

Super-refractory status epilepticus in a 29-year-old pregnant female

SAGE Open Medical Case Reports, 2021
Super-refractory status epilepticus is a rare medical and neurological emergency due to the high mortality and morbidity associated with this condition.
Cinthya Carrasco, Audra Schwalk, Byungkwan Hwang, Kenneth Iwuji, Ebtesam Islam   +4 more
doaj   +1 more source

Neuromodulation in new-onset refractory status epilepticus

Frontiers in Neurology, 2023
Background New-onset refractory status epilepticus (NORSE) and its subset of febrile infection-related epilepsy syndrome (FIRES) are devastating clinical presentations with high rates of mortality and morbidity.
I. Stavropoulos, Jin Han Khaw, A. Valentín   +2 more
semanticscholar   +1 more source

Ketamine for Management of Neonatal and Pediatric Refractory Status Epilepticus

Neurology, 2022
Background and Objectives Few data are available regarding the use of anesthetic infusions for refractory status epilepticus (RSE) in children and neonates, and ketamine use is increasing despite limited data.
M. Jacobwitz, Caitlyn Mulvihill, M. Kaufman, Alexander K. Gonzalez, K. Reséndiz, J. Macdonald, C. Francoeur, I. Helbig, A. Topjian, N. Abend   +9 more
semanticscholar   +1 more source

Intravenous ganaxolone for the treatment of refractory status epilepticus: Results from an open‐label, dose‐finding, phase 2 trial

Epilepsia, 2022
Patients with refractory status epilepticus (RSE) have failed treatment with benzodiazepines and ≥1 second‐line intravenous (IV) antiseizure medication (ASM).
H. Vaitkevicius, R. Ramsay, Christa B. Swisher, A. Husain, A. Aimetti, M. Gąsior   +5 more
semanticscholar   +1 more source

Stiripentol in refractory status epilepticus [PDF]

Epilepsia, 2013
SummaryBenzodiazepines (BZDs), which enhance γ‐aminobutyric acid (GABAA) receptor–mediated inhibition, are the first‐line therapy for treatment of status epilepticus (SE). However, pharmacoresistance toBZDs develops rapidly afterSEinitiation. This is due to an activity‐dependent internalization ofBZD‐sensitiveGABAAreceptors duringSE.
Denise K. Grosenbaugh, David D. Mott
openaire   +3 more sources