Results 51 to 60 of about 10,949 (215)

Vagus nerve stimulation in super-refractory status epilepticus following hypoxic brain injury: a case report and review of the literature

Interdisciplinary Neurosurgery
Background: Status epilepticus (SE) is a life-threatening neurological condition that can be resistant to pharmacological treatments, particularly when triggered by severe brain insults such as asphyxia.
Farzan Fahim, Mahdi Mehmandoost, Faezeh Mousavinia, Amirmohammad Bahri, Negin Safari Dehnavi, Almirabbas Rouholamini, Omidreza Nikbakhtamirabad, Parisa Nikbakhtamirabad, Diba Akbarzadeh, Sayeh Oveisi, Yousef Moghadasi, Alireza Zali, Bijan Herfedoustbiazar   +12 more
doaj   +1 more source

Neonatal Seizures in Tuberous Sclerosis Complex: A Case Series

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Background Epilepsy affects up to 90% of patients with tuberous sclerosis complex (TSC); earlier seizure onset is associated with worse neurocognitive outcomes. The incidence of neonatal seizures in TSC is unknown, although in a recent multicenter trial 23% of infants with TSC were excluded prior to randomization because of pre‐existing ...
Kristina Jülich, Kristen Arredondo
wiley   +1 more source

Treatment of Status Epilepticus [PDF]

Journal of Neurocritical Care, 2016
Status epilepticus is a severe neurological disease associated with substantial mortality and health-care cost. Treatment of status epilepticus should proceed without delay even in the pre-hospital setting because prolonged generalized convulsive ...
Gha-Hyun Lee, Dae Soo Jung
doaj   +1 more source

Intravenous ganaxolone in pediatric super-refractory status epilepticus: A single hospital experience

Epilepsy & Behavior Reports, 2022
Synaptic GABAA receptor (GABAAR) internalization contributes to the drug resistant nature of super-refractory status epilepticus (SRSE). Ganaxolone is a 3β-methylated synthetic analog of the endogenous neuroactive steroid, allopregnanolone, that has ...
Rani K. Singh, Rajdeep Singh, Alejandra Stewart, Katherine Van Poppel, Sarah Klinger, Joseph Hulihan, Heather Van Heusen, Henrikas Vaitkevicius, Maciej Gasior   +8 more
doaj   +1 more source

Steroids for Drug‐Resistant Seizures and Prolonged Stroke‐Like Episode in a Patient With Sturge–Weber Syndrome: A Case Report

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Introduction Sturge–Weber syndrome (SWS) brain involvement has been associated with impairments in the blood–brain barrier (BBB) and microglial activation within involved cortical regions. Acute neurological crises, including seizures, stroke‐like episodes, and/or significant headaches, are common in these patients.
Brenna N. Keam, Fabiola A. Morales‐Vias, Siddharth S. Gupta, Doris D. Lin, Anne M. Comi   +4 more
wiley   +1 more source

Epilepsy characteristics in patients with muscle‐eye‐brain disease: A systematic review of electroclinical features

Epileptic Disorders, EarlyView.
Abstract Background and Objectives Muscle‐Eye‐Brain disease (MEB) is a dystroglycanopathy that belongs to the congenital muscular dystrophies. Central nervous system manifestations include congenital brain abnormalities, neurodevelopmental delay, and epilepsy, making it a rare but important cause of developmental and epileptic encephalopathy.
Stefania Kalampokini, Evripidis Pityrigkas, Eleni Liouta, Georgia Pepe, Vasiliki Poulidou, Martha Spilioti, Vasilios K. Kimiskidis   +6 more
wiley   +1 more source

A guide to neuromodulation in drug‐resistant epilepsy

Epileptic Disorders, EarlyView.
Abstract Neuromodulation is approved for the treatment of drug‐resistant epilepsy. It has been increasingly utilized over the past two decades with the approval of deep brain stimulation (DBS) and responsive neurostimulation (RNS) in addition to vagus nerve stimulation (VNS)—particularly in patients who are not deemed to be good resective surgical ...
Prachi Parikh, Irena Dolezawa, Manu Hegde, Lukas Imbach, Brian N. Lundstrom, Francesca Pizzo, Vikram R. Rao, Jaysingh Singh, Derek Southwell, Satsuke Watanabe, Birgit Frauscher   +10 more
wiley   +1 more source

Cardiac injury in refractory status epilepticus [PDF]

Epilepsia, 2012
SummaryPurpose:  We sought to describe the spectrum of cardiac injury in refractory status epilepticus (RSE).Methods:  We reviewed all patients with RSE between 1999 and 2011 at Mayo Clinic. RSE was defined as generalized convulsive or nonconvulsive status epilepticus (SE) that continued despite initial therapies.
Sara, Hocker, Abhiram, Prasad, Alejandro A, Rabinstein   +2 more
openaire   +2 more sources

Surgical treatment of focal symptomatic refractory status epilepticus with and without invasive EEG

Epilepsy and Behavior Case Reports, 2015
Purpose: Neurosurgery appears to be a reasonable alternative in carefully selected patients with refractory status epilepticus (RSE) and super-refractory status epilepticus (SRSE).
Carolina Cuello Oderiz, Marina Aberastury, Ana Gabriela Besocke, Jorge Sinner, Betiana Comas-Guerrero, Carlos Alberto Ciraolo, Maria Concepción Pasteris, Walter Horacio Silva, María del Carmen García   +8 more
doaj   +1 more source

Seminars in epileptology: Holistic management of epilepsy in adults with intellectual development disorders

Epileptic Disorders, EarlyView.
Abstract This seminar addresses the complexity of the management of epilepsy in adults with intellectual development disorders (IDD), advocating holistic and multidisciplinary care aligned with the learning objectives of the International League Against Epilepsy. Epilepsy is significantly more prevalent in people with IDD, presenting unique diagnostic,
Elena Fonseca, Antonella Riva, Samuel López‐Maza, Malin Zaddach, Marie‐Claire Porter, Ingo Borggraefe, Lance Watkins, Andreas Schulze‐Bonhage, Rohit Shankar, Pasquale Striano, Lina Nashef   +10 more
wiley   +1 more source