Results 191 to 200 of about 344,918 (305)

A phase 1 evaluation of inhaled oxytocin: Physiologically‐based pharmacokinetic model informed dosing of a novel heat‐stable oxytocin delivery system

British Journal of Clinical Pharmacology, EarlyView.
Aim To develop and validate a physiologically‐based pharmacokinetic (PBPK) model enabling inhaled oxytocin dose selection for clinical evaluation. Subsequently, to conduct a phase 1 study investigating the pharmacokinetics and safety of selected doses of an optimized inhaled oxytocin product in healthy, non‐pregnant female participants.
Pete Lambert, Carl M. J. Kirkpatrick, Rory Marriott, Siladitya Ray Chaudhuri, David Polidori, Bart Remmerie, Michelle P. McIntosh   +6 more
wiley   +1 more source

Impact of ice pack quantity and external temperature on chicken meat freshness during distribution in insulated boxes. [PDF]

Food Sci Anim Resour
Kim BM, Kang GS, Lee ES, Kim JH, Shin D, Oh MH.   +5 more
europepmc   +1 more source

Affinity Peptides With pH Sensitivity for the Enrichment of CD38+ Cells

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The selective enrichment of cell populations based on surface markers is critical for the advancement of gene and cell therapies. Current antibody‐based cell isolation methods, such as fluorescence‐ and magnetic‐activated cell sorting (FACS and MACS), offer high specificity but are limited by scalability, cost, and potential adverse effects on
Gabrielle Rusch, Mickael Meyer, I. Mohamed Irfan, Carson Huber, Joseph Burclaff, Scott T. Magness, Stefano Menegatti, Michael Daniele   +7 more
wiley   +1 more source

The effect of storage temperature and time before centrifugation on coagulation parameters in neonatal Japanese Black calves. [PDF]

J Vet Med Sci
Ito R, Sanada K, Inoue S, Maehara T, Satoh H.   +4 more
europepmc   +1 more source

Eudragit®‐engineered pH‐responsive probiotic microspheres with enhanced gastrointestinal resistance and prolonged storage stability for inflammatory bowel disease therapy

BMEMat, EarlyView.
This study reports the development of AMS@Eud core‐shell microspheres, combining calcium alginate and pH‐responsive Eudragit® L100, which exhibit exceptional gastrointestinal resistance and long‐term storage stability (only 5.28%–9.09% viability loss over 35 days at 4–25°C), and effectively alleviate inflammatory bowel disease via gut microbiota ...
Ming Teng, Xiaomin Luo, Peng Zhang, Chen Yang, Yuniel Ma, Xinhua Liu   +5 more
wiley   +1 more source

Multifunctional hyaluronic acid hydrogel integrating exosome‐encapsulating gelatin microspheres accelerates skeletal muscle regeneration via TGF‐β1 activation and enhanced myogenic cell viability

BMEMat, EarlyView.
Schematic illustration of preparation of injectable H/G@Co@miR‐206 hydrogel for efficient skeletal muscle regeneration in cardiotoxin‐induced skeletal muscle injury SD rat model. Abstract The effective treatment of acute skeletal muscle injuries remains challenging, necessitating therapeutic strategies that concurrently reestablish vascular perfusion ...
Zhengzhe Han, Zongyue Li, Ang Li, Zheng Jiang, Saiyu Shi, Zhipeng Wang, Jishizhan Chen, Yun Qian, Yuanyang Gu, Xianyou Zheng   +9 more
wiley   +1 more source

Determination of bisphenol a in doogh (a yogurt-based Iranian drink) by magnetic-SPE (MWCNT-Fe₃O₄)/GC-MS method and human health risk assessment. [PDF]

Sci Rep
Rezapour Z, Arabameri M, Shariatifar N, Hamedi H.   +3 more
europepmc   +1 more source

Debunking the Myth: A Dive Into the Role of Relational Capital in Sustainable Food Production Systems

Business Strategy and the Environment, EarlyView.
ABSTRACT The shift towards sustainable food production is essential to address the urgent dual challenges of climate change and population growth, with agricultural cooperatives playing a vital role in this transformation. However, many cooperatives struggle to deliver the expected value to their members.
Ismail Badraoui, Tarik Saikouk, Nejib Fattam, Ahmed Hamdi, Vikas Kumar   +4 more
wiley   +1 more source

Improving emulsifying properties by high-voltage electrostatic field in emulsified pork batter as phosphate-replacement. [PDF]

Anim Biosci
Liu YT, Yan HZ, Huang CW, Ndlandla TW, Cheng FY.   +4 more
europepmc   +1 more source

Barriers and Enablers of Circular Economy in Electrical and Electronic Equipment: A Systematic Literature Review

Business Strategy and the Environment, EarlyView.
ABSTRACT Rapid technological change, shorter lifecycles and rising demand for electrical and electronic equipment (EEE) are increasing waste electrical and electronic equipment (WEEE) and emphasise the need for a circular economy. This paper identifies barriers and enablers of the circular transition in EEE and outlines interventions.
Aya Abdelmeguid, Lucia Corsini
wiley   +1 more source