DOT1L safeguards cartilage homeostasis and protects against osteoarthritis
DOT1L is one of the few genes linked to osteoarthritis by human GWAS. Here the authors show that DOT1L-dependent histone methylation protects homeostasis of articular chondrocytes by SIRT1-dependent inhibition of canonical WNT signalling, and that ...
Silvia Monteagudo+7 more
doaj +1 more source
Key Trends and Insights in Smart Polymeric Skin Wearable Patches
Intelligent polymers, which respond to various physical and biological stimuli, are explored for the development of skin wearable patches in biomedical applications. Smart polymers, also known as intelligent or stimuli‐responsive polymers, play a crucial role in the development of advanced wearable patches due to their versatility and softness.
Sergio J. Peñas‐Núñez+2 more
wiley +1 more source
Physical Exercise and Cardiac Repair: The Potential Role of Nitric Oxide in Boosting Stem Cell Regenerative Biology [PDF]
Fabiola Marino+8 more
openalex +1 more source
Mesoporous bioactive glass nanoparticles (MBGNs) are investigated for bone regeneration given their remarkable structural and functional properties. MBGNs are functionalized with Mn and Cu and incorporated with quercetin, a natural flavonoid exhibiting antioxidant, anti‐inflammatory, and antimicrobial properties.
Giovanni Lo Bello+5 more
wiley +1 more source
Pivotal Role of Lnk Adaptor Protein in Endothelial Progenitor Cell Biology for Vascular Regeneration [PDF]
Sang‐Mo Kwon+13 more
openalex +1 more source
Improved 3D Printing and Cell Biology Characterization of Inorganic-Filler Containing Alginate-Based Composites for Bone Regeneration: Particle Shape and Effective Surface Area Are the Dominant Factors for Printing Performance [PDF]
Vera Bednarzig+5 more
openalex +1 more source
Control of perennial weeds based on weed biology and environmental considerations [PDF]
Timing, type and duration of tillage operations and cropping practices are of importance for reducing the regeneration of perennial weeds and also for minimizing the environmental impacts of such operations.
Brandsæter, L.O.+3 more
core
Predicted genetic consequences of asexuality include high intraindividual genetic diversity (i.e., the Meselson effect) and accumulation of deleterious mutations (i.e., Muller’s Ratchet), among others.
Leria, L.+3 more
core +1 more source
3D Bioprinting of Thick Adipose Tissues with Integrated Vascular Hierarchies
An advanced 3D bioprinting technique is used here to create thick adipose tissues with a central, vessel and extensive branching. The construct is made using alginate, gelatin and collagen‐based bioinks. Flow through the complex vessel network is demonstrated as well as its successful integration with a femoral artery following implantation in a rat ...
Idit Goldfracht+5 more
wiley +1 more source
Regenerative patterning in Swarm Robots: mutual benefits of research in robotics and stem cell biology [PDF]
Michael Rubenstein+3 more
openalex +1 more source