Results 141 to 150 of about 1,651,358 (339)

Hippo signalling in the liver: role in development, regeneration and disease

Nature reviews: Gastroenterology & hepatology, 2022
Jacquelyn O. Russell, F. Camargo
semanticscholar   +1 more source

Photothermal Hydrogel with Mn3O4 Nanoparticles Alleviates Intervertebral Disc Degeneration by Scavenging ROS and Regulating Extracellular Matrix Metabolism

Advanced Functional Materials, EarlyView.
The MPTT‐nanozyme‐hydrogel system (Mn3O4@ChS‐HA) provides a multifunctional therapeutic strategy for intervertebral disc degeneration (IVDD), effectively targeting oxidative stress and enhancing AF repair by restoring extracellular matrix (ECM) and redox homeostasis.
Yangyang Chen, Chan Xue, Feifei Ni, Binwu Hu, Miaoheng Yan, He Zhang, Yuxiang Hu, Xiaoyao Peng, Guangfang Li, Yu Han, Hongjian Liu, Zengwu Shao, Qin Wang, Yulong Wei   +13 more
wiley   +1 more source

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source

Breaking the Capacity Limit for WO3 Anode‐Based Li‐Ion Batteries Using Photo‐Assisted Charging

Advanced Functional Materials, EarlyView.
This image illustrates a photo‐assisted rechargeable lithium‐ion battery. (a) shows the battery structure, where light enhances electron‐hole generation in the anode, boosting ion flow. (b) compares discharging performance, revealing over 60% higher capacity under light compared to dark conditions, showcasing the benefit of light‐assisted energy ...
Rabia Khatoon, Mudasar Nazir, Richard T. Baker, Mathew Billing, Shumaila Babar, Suela Kellici, Steve Dunn, Muhammad Tariq Sajjad   +7 more
wiley   +1 more source

Harnessing beta cell regeneration biology for diabetes therapy

Trends in Endocrinology & Metabolism
The pandemic scale of diabetes mellitus is alarming, its complications remain devastating, and current treatments still pose a major burden on those affected and on the healthcare system as a whole. As the disease emanates from the destruction or dysfunction of insulin-producing pancreatic β-cells, a real cure requires their restoration and protection.
Stephanie Bourgeois, Sophie Coenen, Laure Degroote, Lien Willems, Annelore Van Mulders, Julie Pierreux, Yves Heremans, Nico De Leu, Willem Staels   +8 more
openaire   +2 more sources

Versatile Cell Penetrating Peptide for Multimodal CRISPR Gene Editing in Primary Stem Cells

Advanced Functional Materials, EarlyView.
CRISPR machinery in diverse molecular formats (DNA, RNA, and ribonucleic protein) is complexed into nanoparticles with the cell‐friendly arginine‐alanine‐leucine‐alanine (RALA) cell‐penetrating peptide. Nanoparticles are delivered to primary mesenchymal stem cells ex vivo or locally in vivo to facilitate multimodal CRISPR gene editing. This RALA‐CRISPR
Joshua P. Graham, Jose Gabriel Castro, Lisette C. Werba, Joseph Amitrano, Luke Fardone, Kevin P. Francis, Anand Ramamurthi, Michael J. Layden, Helen O. McCarthy, Tomas Gonzalez‐Fernandez   +9 more
wiley   +1 more source

The Biology of Regeneration Failure and Success After Spinal Cord Injury.

Physiological Reviews, 2018
A. Tran, P. Warren, J. Silver
semanticscholar   +1 more source

Transient Stiffness Patterning in Hydrogels Driven by Dissipative Mechanochemical Coupling

Advanced Functional Materials, EarlyView.
Force‐induced disulfide bond rupture in a polymer‐based hydrogel, coupled with chemical or electrochemical reoxidation, leads to the transient modulation of the hydrogel's stiffness properties. High spatiotemporal control is achieved by this dissipative process, enabling the development of out‐of‐equilibrium stiffness patterns and transient, dose ...
Roberto Baretta, Maria F. Pantano, Marco Frasconi   +2 more
wiley   +1 more source

Biomimetic Nanomedicines Deliver Naringin for Enhanced Acute Liver Failure Therapy via Balanced Regulation of Hepatocyte Oxidative Stress and Kupffer Cell Inflammation

Advanced Functional Materials, EarlyView.
A biomimetic nanomedicine (RBLN) constructed by loading natural antioxidants to clinically used layered double hydroxide nanoparticles is surface coated with fresh or senescent red blood cell membrane for balanced drug delivery to hepatocytes and KCs, thereby simultaneously alleviating liver oxidant stress and inflammation for effective drug‐induced ...
Jiahui Shao, Maoze Wang, Jinling Huang, Yu Wang, Jing Zhao, Ran Wang, Zhi Ping Xu, Jianping Jiang, Lingxiao Zhang   +8 more
wiley   +1 more source

Synthetic Biology: Rational Pathway Design for Regenerative Medicine [PDF]

, 2015
Jamie A. Davies
openalex   +1 more source