Results 41 to 50 of about 448,418 (302)

Publisher Correction: Exploring the effect of UV-C radiation on earthworm and understanding its genomic integrity in the context of H2AX expression

open access: yesScientific Reports, 2021
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Karthikeyan Subbiahanadar Chelladurai   +12 more
doaj   +1 more source

Nerve commitment in Hydra. I. Role of morphogenetic signals [PDF]

open access: yes, 1981
The kinetics of nerve commitment during head regeneration in Hydra were investigated using a newly developed assay for committed cells. Committed nerve precursors were assayed by their ability to continue nerve differentiation following explanation of ...
Berking   +25 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Falsely normalized ankle-brachial index despite the presence of lower-extremity peripheral artery disease: two case reports

open access: yesJournal of Medical Case Reports, 2021
Background The ankle-brachial index measurement is used for screening and diagnosis of lower-extremity peripheral artery disease and cardiovascular risk assessment.
Tatsuya Maruhashi   +5 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Transplantation of Embryonic and Induced Pluripotent Stem Cell-Derived 3D Retinal Sheets into Retinal Degenerative Mice

open access: yesStem Cell Reports, 2014
In this article, we show that mouse embryonic stem cell- or induced pluripotent stem cell-derived 3D retinal tissue developed a structured outer nuclear layer (ONL) with complete inner and outer segments even in an advanced retinal degeneration model ...
Juthaporn Assawachananont   +7 more
doaj   +1 more source

HDAC4 regulates skeletal muscle regeneration via soluble factors [PDF]

open access: yes, 2018
Skeletal muscle possesses a high ability to regenerate after an insult or in pathological conditions, relying on satellite cells, the skeletal muscle stem cells.
Alessandra Renzini   +5 more
core   +3 more sources

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Application of Computational Methods in Planaria Research: A Current Update

open access: yesJournal of Integrative Bioinformatics, 2017
Planaria is a member of the Phylum Platyhelminthes including flatworms. Planarians possess the unique ability of regeneration from adult stem cells or neoblasts and finds importance as a model organism for regeneration and developmental studies. Although
Ghosh Shyamasree
doaj   +1 more source

Modulation of TNFα Activity by the microRNA Let-7 Coordinates Zebrafish Heart Regeneration

open access: yesiScience, 2019
Summary: The adult zebrafish is capable of regenerating heart muscle, resolving collagen tissue, and fully restoring heart function throughout its life. In this study, we show that the highly upregulated, epicardium-enriched microRNA let-7i functions in ...
Ashley M. Smith   +3 more
doaj   +1 more source

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