Results 41 to 50 of about 190,601 (304)

From Cell Death to Regeneration: Rebuilding After Injury

, 2021
The ability to regrow lost or damaged tissues is widespread, but highly variable among animals. Understanding this variation remains a challenge in regeneration biology.
Tseng, Kelly, Kha, Cindy, Guerin, Dylan
core   +1 more source

Publisher Correction: Exploring the effect of UV-C radiation on earthworm and understanding its genomic integrity in the context of H2AX expression

Scientific Reports, 2021
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Karthikeyan Subbiahanadar Chelladurai, Jackson Durairaj Selvan Christyraj, Ananthaselvam Azhagesan, Vennila Devi Paulraj, Muralidharan Jothimani, Beryl Vedha Yesudhason, Niranjan Chellathurai Vasantha, Mijithra Ganesan, Kamarajan Rajagopalan, Saravanakumar Venkatachalam, Johnson Benedict, Jemima Kamalapriya John Samuel, Johnson Retnaraj Samuel Selvan Christyraj   +12 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Evolution, comparative biology and ontogeny of vertebrate heart regeneration [PDF]

npj Regenerative Medicine, 2016
AbstractThere are 64,000 living species of vertebrates on our planet and all of them have a heart. Comparative analyses devoted to understanding the regenerative potential of the myocardium have been performed in a dozen vertebrate species with the aim of developing regenerative therapies for human heart disease.
Vivien, CJ, Hudson, JE, Porrello, ER
openaire   +7 more sources

Modulation of TNFα Activity by the microRNA Let-7 Coordinates Zebrafish Heart Regeneration

iScience, 2019
Summary: The adult zebrafish is capable of regenerating heart muscle, resolving collagen tissue, and fully restoring heart function throughout its life. In this study, we show that the highly upregulated, epicardium-enriched microRNA let-7i functions in ...
Ashley M. Smith, Christina A. Dykeman, Benjamin L. King, Viravuth P. Yin   +3 more
doaj   +1 more source

Falsely normalized ankle-brachial index despite the presence of lower-extremity peripheral artery disease: two case reports

Journal of Medical Case Reports, 2021
Background The ankle-brachial index measurement is used for screening and diagnosis of lower-extremity peripheral artery disease and cardiovascular risk assessment.
Tatsuya Maruhashi, Shogo Matsui, Farina Mohamad Yusoff, Shinji Kishimoto, Masato Kajikawa, Yukihito Higashi   +5 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Application of Computational Methods in Planaria Research: A Current Update

Journal of Integrative Bioinformatics, 2017
Planaria is a member of the Phylum Platyhelminthes including flatworms. Planarians possess the unique ability of regeneration from adult stem cells or neoblasts and finds importance as a model organism for regeneration and developmental studies. Although
Ghosh Shyamasree
doaj   +1 more source

Transplantation of Embryonic and Induced Pluripotent Stem Cell-Derived 3D Retinal Sheets into Retinal Degenerative Mice

Stem Cell Reports, 2014
In this article, we show that mouse embryonic stem cell- or induced pluripotent stem cell-derived 3D retinal tissue developed a structured outer nuclear layer (ONL) with complete inner and outer segments even in an advanced retinal degeneration model ...
Juthaporn Assawachananont, Michiko Mandai, Satoshi Okamoto, Chikako Yamada, Mototsugu Eiraku, Shigenobu Yonemura, Yoshiki Sasai, Masayo Takahashi   +7 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source