Results 21 to 30 of about 190,601 (304)
Elly Tanaka's passion for exploring animal regeneration. [PDF]
, 2018 This interview, performed by the guest editors of this Int. J. Dev. Biol. Special Issue on Regeneration, narrates the story of Elly M. Tanaka on her regeneration research journey.
Mercader Huber, Nadia Isabel +1 more
core +1 more source
Stem Cell Reports, 2014 Age-related macular degeneration (AMD) causes severe visual impairment due in part to age-dependent impairment of retinal pigment epithelium (RPE). It has been suggested that autologous human induced pluripotent stem cells (hiPSCs) may represent a useful
Hiroyuki Kamao +7 more
doaj +1 more source
The role of roof plate-specific spondins in liver homeostasis and disease
Liver Research, 2022 As evolutionarily conserved signals, roof plate-specific spondins (R-spondins; RSPOs) are a family with four members (RSPO1–4) exerting distinctly different functions.
Le Yang +5 more
doaj +1 more source
Tissue repair brakes: A common paradigm in the biology of regeneration [PDF]
Stem Cells, 2019 Abstract To date, most attention on tissue regeneration has focused on the exploration of positive cues promoting or allowing the engagement of natural cellular restoration upon injury. In contrast, the signals fostering cell identity maintenance in the vertebrate body have been poorly investigated; yet they are crucial, for their ...
Valentina Cigliola +3 more
openaire +3 more sources
The basis of liver regeneration: A systems biology approach
Annals of Hepatology, 2018 Introduction and aim. Liver regeneration is a normal response to liver injury. The aim of this study was to determine the molecular basis of liver regeneration, through an integrative analysis of high-throughput gene expression datasets. Material and methods.
Mamatha Bhat +7 more
openaire +3 more sources
Germplasm Conservation: Instrumental in Agricultural Biodiversity—A Review
, 2021 Germplasm is a valuable natural resource that provides knowledge about the genetic composition of a species and is crucial for conserving plant diversity. Germplasm protection strategies not only involve rescuing plant species threatened with extinction,
Prashant Kaushik +3 more
core +1 more source
Regeneration Roadmap: database resources for regenerative biology.
Nucleic acids research, 2021 Regeneration plays an instrumental role in biological development and damage repair by constructing and replacing cells, tissues, and organs. Since regenerative capacity declines with age, promoting regeneration is heralded as a potential strategy for delaying aging.
Kang, Wang +16 more
openaire +2 more sources
Mediators of Inflammation, 2019 As adult mammals lack the capacity to replace or repair damaged neurons, degeneration and trauma (and subsequent dysfunction) of the central nervous system (CNS) seriously constrains the patient’s life quality.
Ilse Bollaerts +6 more
doaj +1 more source
Frontiers in Immunology, 2017 Macrophage M1/M2 polarization mediates tissue damage and inflammatory responses. Cannabinoid receptor (CB) 1 participated in liver fibrogenesis by affecting bone marrow (BM)-derived monocytes/macrophages (BMMs) activation.
Lei Tian +8 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source