Protein transduction: A novel tool for tissue regeneration [PDF]
Tissue regeneration in humans is limited and excludes vitals organs like heart and brain. Transformation experiments with oncogenes like T antigen have shown that retrodifferentiation of the respective cells is possible but hard to control. To bypass the
Cardoso, M. C. +4 more
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The Teleost Retina as a Model for Developmental and Regeneration Biology [PDF]
Retinal development in teleosts can broadly be divided into three epochs. The first is the specification of cellular domains in the larval forebrain that give rise to the retinal primordia and undergo early morphogenetic movements. The second is the neurogenic events within the retina proper-proliferation, cell fate determination, and pattern formation-
Hitchcock, Peter F., Raymond, Pamela A.
openaire +3 more sources
Thyrotropin-releasing hormone (TRH) promotes wound re-epithelialisation in frog and human skin [PDF]
There remains a critical need for new therapeutics that promote wound healing in patients suffering from chronic skin wounds. This is, in part, due to a shortage of simple, physiologically and clinically relevant test systems for investigating candidate ...
Paredes Roberto +59 more
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Age-related macular degeneration (AMD) causes severe visual impairment due in part to age-dependent impairment of retinal pigment epithelium (RPE). It has been suggested that autologous human induced pluripotent stem cells (hiPSCs) may represent a useful
Hiroyuki Kamao +7 more
doaj +1 more source
The role of roof plate-specific spondins in liver homeostasis and disease
As evolutionarily conserved signals, roof plate-specific spondins (R-spondins; RSPOs) are a family with four members (RSPO1–4) exerting distinctly different functions.
Le Yang +5 more
doaj +1 more source
Liver Development, Regeneration, and Carcinogenesis [PDF]
The identification of putative liver stem cells has brought closer the previously separate fields of liver development, regeneration, and carcinogenesis. Significant overlaps in the regulation of these processes are now being described.
Ross, James A +7 more
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Tissue repair brakes: A common paradigm in the biology of regeneration [PDF]
Abstract To date, most attention on tissue regeneration has focused on the exploration of positive cues promoting or allowing the engagement of natural cellular restoration upon injury. In contrast, the signals fostering cell identity maintenance in the vertebrate body have been poorly investigated; yet they are crucial, for their ...
Valentina Cigliola +3 more
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The dynamics of alkaline phosphatase activity during operculum regeneration in the polychaete Pomatoceros lamarckii [PDF]
RS is supported by a Carnegie Scholarship. Date of Acceptance: 20/06/2014Alkaline phosphatase enzymes are found throughout the living world and fulfil a variety of functions.
Ferrier, David Ellard Keith, Szabo, Reka
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The basis of liver regeneration: A systems biology approach
Introduction and aim. Liver regeneration is a normal response to liver injury. The aim of this study was to determine the molecular basis of liver regeneration, through an integrative analysis of high-throughput gene expression datasets. Material and methods.
Mamatha Bhat +7 more
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Cell proliferation dynamics in regeneration of the operculum head appendage in the annelid Pomatoceros lamarckii [PDF]
Regeneration of lost or damaged appendages is a widespread and ecologically important ability in the animal kingdom, and also of great significance to developing regenerative medicine.
Réka Szabó +3 more
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