Results 21 to 30 of about 1,870,035 (300)

Protein transduction: A novel tool for tissue regeneration [PDF]

open access: yes, 2002
Tissue regeneration in humans is limited and excludes vitals organs like heart and brain. Transformation experiments with oncogenes like T antigen have shown that retrodifferentiation of the respective cells is possible but hard to control. To bypass the
Cardoso, M. C.   +4 more
core   +2 more sources

The Teleost Retina as a Model for Developmental and Regeneration Biology [PDF]

open access: yesZebrafish, 2004
Retinal development in teleosts can broadly be divided into three epochs. The first is the specification of cellular domains in the larval forebrain that give rise to the retinal primordia and undergo early morphogenetic movements. The second is the neurogenic events within the retina proper-proliferation, cell fate determination, and pattern formation-
Hitchcock, Peter F., Raymond, Pamela A.
openaire   +3 more sources

Thyrotropin-releasing hormone (TRH) promotes wound re-epithelialisation in frog and human skin [PDF]

open access: yes, 2013
There remains a critical need for new therapeutics that promote wound healing in patients suffering from chronic skin wounds. This is, in part, due to a shortage of simple, physiologically and clinically relevant test systems for investigating candidate ...
Paredes Roberto   +59 more
core   +2 more sources

Characterization of Human Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium Cell Sheets Aiming for Clinical Application

open access: yesStem Cell Reports, 2014
Age-related macular degeneration (AMD) causes severe visual impairment due in part to age-dependent impairment of retinal pigment epithelium (RPE). It has been suggested that autologous human induced pluripotent stem cells (hiPSCs) may represent a useful
Hiroyuki Kamao   +7 more
doaj   +1 more source

The role of roof plate-specific spondins in liver homeostasis and disease

open access: yesLiver Research, 2022
As evolutionarily conserved signals, roof plate-specific spondins (R-spondins; RSPOs) are a family with four members (RSPO1–4) exerting distinctly different functions.
Le Yang   +5 more
doaj   +1 more source

Liver Development, Regeneration, and Carcinogenesis [PDF]

open access: yes, 2010
The identification of putative liver stem cells has brought closer the previously separate fields of liver development, regeneration, and carcinogenesis. Significant overlaps in the regulation of these processes are now being described.
Ross, James A   +7 more
core   +1 more source

Tissue repair brakes: A common paradigm in the biology of regeneration [PDF]

open access: yesStem Cells, 2019
Abstract To date, most attention on tissue regeneration has focused on the exploration of positive cues promoting or allowing the engagement of natural cellular restoration upon injury. In contrast, the signals fostering cell identity maintenance in the vertebrate body have been poorly investigated; yet they are crucial, for their ...
Valentina Cigliola   +3 more
openaire   +3 more sources

The dynamics of alkaline phosphatase activity during operculum regeneration in the polychaete Pomatoceros lamarckii [PDF]

open access: yes, 2014
RS is supported by a Carnegie Scholarship. Date of Acceptance: 20/06/2014Alkaline phosphatase enzymes are found throughout the living world and fulfil a variety of functions.
Ferrier, David Ellard Keith, Szabo, Reka
core   +1 more source

The basis of liver regeneration: A systems biology approach

open access: yesAnnals of Hepatology, 2018
Introduction and aim. Liver regeneration is a normal response to liver injury. The aim of this study was to determine the molecular basis of liver regeneration, through an integrative analysis of high-throughput gene expression datasets. Material and methods.
Mamatha Bhat   +7 more
openaire   +3 more sources

Cell proliferation dynamics in regeneration of the operculum head appendage in the annelid Pomatoceros lamarckii [PDF]

open access: yes, 2014
Regeneration of lost or damaged appendages is a widespread and ecologically important ability in the animal kingdom, and also of great significance to developing regenerative medicine.
Réka Szabó   +3 more
core   +1 more source

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