Results 11 to 20 of about 448,418 (302)
Digit Tip Regeneration: Merging Regeneration Biology with Regenerative Medicine. [PDF]
Stem Cells Transl Med, 2018 Summary Regeneration Biology is the study of organisms with endogenous regenerative abilities, whereas Regenerative Medicine focuses on engineering solutions for human injuries that do not regenerate. While the two fields are fundamentally different in their approach, there is an obvious interface involving mammalian regeneration models.
Dolan CP, Dawson LA, Muneoka K.
europepmc +4 more sources
Liver regeneration biology: Implications for liver tumour therapies. [PDF]
World J Clin Oncol, 2021 The liver has remarkable regenerative potential, with the capacity to regenerate after 75% hepatectomy in humans and up to 90% hepatectomy in some rodent models, enabling it to meet the challenge of diverse injury types, including physical trauma, infection, inflammatory processes, direct toxicity, and immunological insults.
Hadjittofi C +4 more
europepmc +3 more sources
Islet Cell Biology, Regeneration, and Transplantation [PDF]
International Journal of Endocrinology, 2012 Research studies centered on the biology, regeneration, and transplantation of islets continue to shed significant understanding on the development of different forms of diabetes and provide further impetus for the quest to find a “cure.” Diabetes is a manifestation of an inadequate mass of insulin-producing pancreatic beta-cells.
A. N. Balamurugan +3 more
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The cell biology of regeneration [PDF]
Journal of Cell Biology, 2012 Regeneration of complex structures after injury requires dramatic changes in cellular behavior. Regenerating tissues initiate a program that includes diverse processes such as wound healing, cell death, dedifferentiation, and stem (or progenitor) cell proliferation; furthermore, newly regenerated tissues must integrate polarity and positional identity ...
King, Ryan S., Newmark, Phillip A.
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A Chemical Biology Approach to Myocardial Regeneration [PDF]
Journal of Cardiovascular Translational Research, 2011 Heart failure is one of the major causes of death in the Western world because cardiac muscle loss is largely irreversible and can lead to a relentless decline in cardiac function. Novel therapies are needed since the only therapy to effectively replace lost myocytes today is transplantation of the entire heart.
Erik Willems +5 more
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Acta Biológica Colombiana, 2021 Ambystoma mexicanum is a urodele amphibian endemic to Xochimilco Lake in Mexico, it belongs to the salamander family Ambystomatidae. This species has frequently been used as model organism in developmental biology and regeneration laboratories around ...
Melisa Hincapie Agudelo +3 more
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Nature Communications, 2020 Mechanisms that regulate epithelial bending mainly link to cell shape changes, for example, the formation of wedge shaped cells. Here, the authors identify a different cell behaviour in the salivary glands and teeth where initial invagination arises by a
Jingjing Li +3 more
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Trials, 2023 Background Rheumatoid arthritis (RA) considerably impacts patients’ lives. Patients’ confidence in their ability to manage this impact, or self-efficacy, can be supported with self-management interventions.
Michaël Doumen +8 more
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Wnt signalling in intestinal stem cells: lessons from mice and flies [PDF]
, 2018 Adult stem cells play critical roles in the basal maintenance of tissue integrity, also known as homeostasis, and in tissue regeneration following damage. The highly conserved Wnt signalling pathway is a key regulator of stem cell fate.
Carroll, Lynsey +2 more
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Regeneration Roadmap: database resources for regenerative biology.
Nucleic acids research, 2021 Regeneration plays an instrumental role in biological development and damage repair by constructing and replacing cells, tissues, and organs. Since regenerative capacity declines with age, promoting regeneration is heralded as a potential strategy for delaying aging.
Kang, Wang +16 more
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