Digit Tip Regeneration: Merging Regeneration Biology with Regenerative Medicine. [PDF]
Summary Regeneration Biology is the study of organisms with endogenous regenerative abilities, whereas Regenerative Medicine focuses on engineering solutions for human injuries that do not regenerate. While the two fields are fundamentally different in their approach, there is an obvious interface involving mammalian regeneration models.
Dolan CP, Dawson LA, Muneoka K.
europepmc +5 more sources
The Teleost Retina as a Model for Developmental and Regeneration Biology [PDF]
Retinal development in teleosts can broadly be divided into three epochs. The first is the specification of cellular domains in the larval forebrain that give rise to the retinal primordia and undergo early morphogenetic movements. The second is the neurogenic events within the retina proper-proliferation, cell fate determination, and pattern formation-
Hitchcock, Peter F., Raymond, Pamela A.
openaire +4 more sources
Liver regeneration biology: Implications for liver tumour therapies. [PDF]
The liver has remarkable regenerative potential, with the capacity to regenerate after 75% hepatectomy in humans and up to 90% hepatectomy in some rodent models, enabling it to meet the challenge of diverse injury types, including physical trauma, infection, inflammatory processes, direct toxicity, and immunological insults.
Hadjittofi C +4 more
europepmc +3 more sources
Islet Cell Biology, Regeneration, and Transplantation [PDF]
Research studies centered on the biology, regeneration, and transplantation of islets continue to shed significant understanding on the development of different forms of diabetes and provide further impetus for the quest to find a “cure.” Diabetes is a manifestation of an inadequate mass of insulin-producing pancreatic beta-cells.
A. N. Balamurugan +3 more
doaj +3 more sources
Artificially altered gravity elicits cell homeostasis imbalance in planarian worms, and cerium oxide nanoparticles counteract this effect [PDF]
Gravity alterations elicit complex and mostly detrimental effects on biological systems. Among these, a prominent role is occupied by oxidative stress, with consequences for tissue homeostasis and development.
Prato, Mirko +32 more
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The cell biology of regeneration [PDF]
Regeneration of complex structures after injury requires dramatic changes in cellular behavior. Regenerating tissues initiate a program that includes diverse processes such as wound healing, cell death, dedifferentiation, and stem (or progenitor) cell proliferation; furthermore, newly regenerated tissues must integrate polarity and positional identity ...
King, Ryan S., Newmark, Phillip A.
openaire +2 more sources
A Chemical Biology Approach to Myocardial Regeneration [PDF]
Heart failure is one of the major causes of death in the Western world because cardiac muscle loss is largely irreversible and can lead to a relentless decline in cardiac function. Novel therapies are needed since the only therapy to effectively replace lost myocytes today is transplantation of the entire heart.
Erik Willems +5 more
openaire +2 more sources
Understanding the epigenetic regulation of stem cell fate in planarians using functional genomics
Planarians owe their remarkable regenerative capabilities to somatic pluripotent stem cells or neoblasts which, as the only dividing cells in the body, are able to differentiate into all cell types.
Sridhar, Divya Lakshmi
core +2 more sources
Sea cucumber fisheries in the Kingdom of Tonga: regeneration biology, ecology, and environmental chemistry [PDF]
The goals of this thesis were to address the environmental and anthropogenic factors which may be influencing sea cucumber decline in the nearshore environment around Tongatapu.
Charan-Dixon, Hannah
core +1 more source
Exercise, Diet and Sleeping as Regenerative Medicine Adjuvants: Obesity and Ageing as Illustrations
Regenerative medicine uses the biological and medical knowledge on how the cells and tissue regenerate and evolve in order to develop novel therapies. Health conditions such as ageing, obesity and cancer lead to an impaired regeneration ability. Exercise,
Mayumi Yoshioka +2 more
core +1 more source

