Results 61 to 70 of about 932,294 (385)
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Performance Analysis of Small Refrigerating Regenerators
Zhileng xuebao, 2015 Heat regenerator formed by capillary and suction pipe has an important influence on the performance of small refrigeration equipment. At present, there are four main types of regenerator: capillary wear type, aluminum foil cover type, copper and tin ...
Sheng wei +3 more
doaj
Measurement of Heat Flow Transmitted through a Stacked-Screen Regenerator of Thermoacoustic Engine
Applied Sciences, 2017 A stacked-screen regenerator is a key component in a thermoacoustic Stirling engine. Therefore, the choice of suitable mesh screens is important in the engine design.
Shu Han Hsu, Tetsushi Biwa
doaj +1 more source
An application of gap regenerator/expander precooled by two stage G-M refrigerator [PDF]
, 1983 The degradation of regenerator effectiveness below 10K is due to the imbalance of the heat capacity of the regenerator material and helium gas as a working fluid.
Matsubara, Y., Yasukochi, K.
core +1 more source
Trends in Neurosciences, 1992 The goal of research on neural regeneration is to restore brain function following injury. To many, this suggests regrowing damaged axons and re-establishing the interrupted pathways. A second, but little studied aspect of brain regeneration, is the replacement of lost neurons.
Hitchcock, Peter F., Raymond, Pamela A.
openaire +3 more sources
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Two Dimensional Thermal-Hydraulic Analysis for a Packed Bed Regenerator Used in a Reheating Furnace
Energies, 2016 Packed bed is widely used for different industries and technologies, such as heat exchangers, heat recovery, thermal energy storage and chemical reactors.
Chien-Nan Lin +2 more
doaj +1 more source
Thermal analysis and optimization of a heat regenerator composed of two coupled moving bed heat exchangers [PDF]
, 2008 This work presents a study to optimize the performance of a heat regenerator composed by two coupled moving bed heat exchangers (MBHE). A MBHE is used to recover heat, from a hot gas stream, and the other one is used to preheat an air stream.
Almendros Ibáñez, José Antonio +3 more
core +2 more sources
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source