Results 141 to 150 of about 5,049,311 (291)

Pleomorphic adenoma arising from ectopic salivary glands in the submandibular region: a case report. [PDF]

J Surg Case Rep
Ikeda Y, Ogawa A, Kawai T, Kogi S, Izumisawa M, Yamada H.   +5 more
europepmc   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Spatiotemporal trends in WBGT and affected population in the MENA region (1951-2021). [PDF]

Sci Rep
Hamed MM, Rady M, Iqbal Z, Nashwan MS, Shahid S.   +4 more
europepmc   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Revista mensual del Centro Región Leonesa: Revista mensual del Centro Región Leonesa - Año II Número 14 - 1920 junio (01/06/1920)

, 1920
Copia digital. Valladolid : Junta de Castilla y León.
Asociación Centro Región Leonesa (Buenos Aires)
core  

Prevalence of asthma and the premature mortality in Eastern sub-Saharan Africa, from 1990 to 2023. [PDF]

SAGE Open Med
Tadesse S, Diriba DC, Berhane A, Lemma H, Dube GN, Hero DD, Sergindo MT.   +6 more
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Model-Dependent Cardiovascular Risk Stratification in Obese Populations: Multicenter Study in Türkiye. [PDF]

Int J Gen Med
Düzen Oflas N, Oral A, Solmaz I, Topaloglu US, Demir I, Dundar A, Kirik A, Kama Başcı O, Sen H, Binnetoglu E, Okuroglu N, Aydin A, Kaya ZI, Yıldız H, Acet A, Tazegül G, Sozel H, Ozudogru O, Issever K, Yaylacı S, Korkmaz UB, Küçük C, Konur K, Ayaz T, Isiklar A, Arac E, Sumbul HE, Öztürk HA, Govez AB, Durmus YÜ, Onmez A, Ocak Serin S, Koca N, Yalcın N, Ertinmaz A, Güven AT, Kok M, Alp HH, Sahinturk Y, Uyar S.   +39 more
europepmc   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Revista mensual del Centro Región Leonesa: Revista mensual del Centro Región Leonesa - Año I Número 5 - 1919 junio (01/06/1919)

, 1919
Copia digital. Valladolid : Junta de Castilla y León.
Asociación Centro Región Leonesa (Buenos Aires)
core