Results 141 to 150 of about 6,134,931 (285)

Back Matter Vol. 19 No.1 (2024)

Region: Jurnal Pembangunan Wilayah dan Perencanaan Partisipatif
Jurnal Region
doaj   +1 more source

Características del virus del dengue y su pronóstico bioclimático en el Departamento de Cortés

Medisan
Se efectuó un estudio observacional, descriptivo y transversal en el Departamento de Cortés, en Honduras, durante el período de 2003 a 2013, con vistas a determinar las características del dengue en esta región, describir su historicidad y desarrollar un
Adrián Palú Orozco, Rafael César García Fernández, Delia Tercero Méndez, Mario Torres Hernández, Lourdes Carolina Estrada   +4 more
doaj  

Habitat imaging based on water-fat separation for interpreting extraocular muscle heterogeneity in thyroid eye disease. [PDF]

Eur Thyroid J
Zhai L, Yin Y, Chen Y, Liang W, Li F, Wang Q, Yuan G, Zhang J.   +7 more
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

A climate region classification for California's warm season: apparent temperature clustering to support heat-health epidemiology. [PDF]

Int J Biometeorol
Villanueva M, Monte-Sano S, Sheridan S, Allen M, Kalkstein L, Jerrett M, Eisenman DP.   +6 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Optimized reference region and the effect on test-retest reliability and sensitivity to differences between Parkinson's disease and control groups with [¹¹C]UCB-J. [PDF]

J Cereb Blood Flow Metab
Khattar N, Matuskey D, Gallezot JD, Naganawa M, Holmes SE, Ebrahimian Sadabad F, Mayeli M, Esterlis I, van Dyck CH, Mecca AP, D'Souza DC, Nabulsi NB, Finnema SJ, Huang Y, Carson RE, Toyonaga T.   +15 more
europepmc   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Optimization of Patient Skin Dose by C-Arm Angulation in Interventional Radiology for Spinal Vascular Lesions. [PDF]

J Neuroendovasc Ther
Tada T, Nishihori M, Sugimoto N, Mukoyama T, Sakai T, Uemura T, Koyama S, Tsutsumi Y, Izumi T, Goto S, Muraoka S, Takeuchi I, Saito R.   +12 more
europepmc   +1 more source